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Mismatch Repair System Proteins In Oral Benign And Malignant Lesions
(Wiley-BlackwellHoboken, 2017)
Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence
(TAYLOR & FRANCIS INC, 2004)
Germ cell tumor (GCT) is the most common genitourinary malignancy of men between the ages of 18 and 35 years. Therapy is ultimately successful in over 90% of patients, however significant morbidity and mortality can be ...
Hypermutation in burkholderia cepacia complex is mediated by DNA mismatch repair inactivation and is highly prevalent in cystic fibrosis chronic respiratory infection
(Elsevier Gmbh, 2014-08)
The Burkholderia cepacia complex (Bcc) represents an important group of pathogens involved in long-term lung infection in cystic fibrosis (CF) patients. A positive selection of hypermutators, linked to antimicrobial ...
Mismatch recognition function of Arabidopsis thaliana MutS-gamma
(Elsevier Science, 2013-02)
Genetic stability depends in part on an efficient DNA lesion recognition and correction by the DNA mismatch repair (MMR) system. In eukaryotes, MMR is initiated by the binding of heterodimeric MutS homologue (MSH) complexes, ...
Simple Sequence Repeats Together with Mismatch Repair Deficiency Can Bias Mutagenic Pathways in Pseudomonas aeruginosa during Chronic Lung Infection
(Public Library Science, 2013-11-21)
Pseudomonas aeruginosa is an opportunistic pathogen that chronically infects the airways of cystic fibrosis (CF) patients and undergoes a process of genetic adaptation based on mutagenesis. We evaluated the role of ...
DNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477)
(Wiley-liss, Div John Wiley & Sons Inc, 2018-12)
MutLα, a heterodimer consisting of MLH1 and PMS2, is a key player of DNA mismatch repair (MMR), yet little is known about its regulation. In this study, we used mass spectrometry to identify phosphorylated residues within ...
Alterações fisiológicas causadas pelo arsênio, genotoxidade e importância do mecanismo mismatch repair no reparo do DNA em Arabidopsis thalianaPhysiological changes caused by arsenic, genotoxicity and importance of mismatch repair mechanism in DNA repair in Arabidopsis thaliana
(Universidade Federal de Viçosa, 2017)
Mismatch repair gene expression and genetic instability in testicular germ cell tumor
(LANDES BIOSCIENCE, 2004)