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Unpredictable chronic mild stress exerts anxiogenic-like effects and activates neurons in the dorsal and caudal region and in the lateral wings of the dorsal raphe nucleus
(Elsevier B. V., 2015-10-17)
In previous studies, we verified that exposure to unpredictable chronic mild stress (UCMS) facilitates avoidance responses in the elevated T-maze (ETM) and increased Fos-immunoreactivity in different brain structures ...
How does early maternal separation and chronic stress in adult rats affect the immunoreactivity of serotonergic neurons within the dorsal raphe nucleus?
(Taylor & Francis Ltd, 2018-01)
Vulnerability to emotional disorders like depression derives from interactions between early and late environments, including stressful conditions. The serotonin (5HT) system is strongly affected by stress and chronic ...
DIFFERENTIAL INVOLVEMENT OF DORSAL RAPHE SUBNUCLEI IN THE REGULATION OF ANXIETY- AND PANIC-RELATED DEFENSIVE BEHAVIORS
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2013-08-02)
A wealth of evidence indicates that the dorsal raphe nucleus (DR) is not a homogenous structure, but an aggregate of distinctive populations of neurons that may differ anatomically, neurochemically and functionally. Other ...
Prefrontal afferents to the dorsal raphe nucleus in the rat
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
The prefrontal cortex (PFC) receives strong inputs from monoaminergic cell groups in the brainstem and also sends projections to these nuclei. Recent evidence suggests that the PFC exerts a powerful top-down control over ...
Posibles alteraciones en el sustrato neurobiológico y conductual provocadas por la separación materna temprana en un modelo animal de depresión: tratamiento con tianeptina
(2018-10-04)
La vulnerabilidad a los trastornos emocionales como la depresión puede surgir a partir de la interacción entre el ambiente temprano y adulto que incluyen componentes estresantes. La separación materna temprana produce ...