Buscar
Mostrando ítems 1-10 de 175
Comparative analysis of loss of heterozygosity and microsatellite instability in adult and pediatric melanoma.
(2005)
Although 0.3% of melanomas occur in children, the incidence has risen in past decades. In adult melanoma, some chromosomal regions in 1p, 6q, 9p, 10q, and 11q are frequently deleted. Microsatellite instability (MSI), which ...
Analysis of genomic instability in adult-onset celiac disease patients by microsatellite instability and loss of heterozygosis
(Lippincott Williams, 2008-12)
Background and Aims: Malignant complications of celiac disease (CD) include carcinomas and lymphomas. The genetic basis behind cancer development in CD is not known, but acquisition of genetic abnormalities and genomic ...
Presence of microsatellite instability in esophageal squamous cell carcinoma associated with chagasic megaesophagus
(2018-06-01)
Aim: The molecular pathogenesis of esophageal squamous cell carcinoma (ESCC) has been increasingly studied, but there is no report on the role of MSI in ESCC development associated with chagasic megaesophagus (CM).Result ...
Mismatch repair expression in testicular cancer predicts recurrence and survival
(WILEY-LISS, 2008)
We investigated mismatch repair (MMR) gene expression in testicular cancer as a molecular marker for clinical outcome (recurrence, response to chemotherapy and death) using protein expression and specific genetic alterations ...
Lynch syndrome: selection of families by microsatellite instability and immunohistochemistry
(SOC MEDICA SANTIAGO, 2012)
Background: Selection of patients with Lynch Syndrome (LS) for a genetic study involves the application of clinical criteria. To increase the rate of identification of mutations, the use of molecular studies as Microsatellite ...
Análisis genético en pacientes con cáncer colorrectalMicrosatellite instability among patients with colorectal cancer
(Sociedad Médica de SantiagoGenética Molecular (GENMOL)Santiago de Chile, Chile, 2022)
Distinct regions of loss of heterozygosity on 22q at different sites of head and neck squamous cell carcinomas
(2002-04-10)
Background: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with ...
Distinct regions of loss of heterozygosity on 22q at different sites of head and neck squamous cell carcinomas
(2002-04-10)
Background: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with ...