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Using the comet and micronucleus assays for genotoxicity studies: a review
(2015)
Physical, chemical and biological agents can act in the DNA, resulting in mutation involved in cancer. Thus, genotoxic tests are required by regulatory agencies in order to evaluate potential risk of cancer. Among these ...
Induction of micronucleus and nuclear alterations in fish (Oreochromis niloticus) by a petroleum
(Elsevier B.V., 2008-10-30)
In this study, micronucleus and nuclear alterations tests were performed on erythrocytes of Oreochromis niloticus (Perciformes, Cichlidae) in order to evaluate the water quality of the Atibaia river, in an area that receives ...
Induction of micronucleus and nuclear alterations in fish (Oreochromis niloticus) by a petroleum
(Elsevier B.V., 2008-10-30)
In this study, micronucleus and nuclear alterations tests were performed on erythrocytes of Oreochromis niloticus (Perciformes, Cichlidae) in order to evaluate the water quality of the Atibaia river, in an area that receives ...
First in vivo evaluation of the mutagenic effect of Brazilian green propolis by comet assay and micronucleus test
(Pergamon-Elsevier B.V. Ltd, 2008-07-01)
Propolis is a hive product containing chiefly beeswax and plant-derived substances such as resin and volatile compounds. Propolis has been used in various parts of the world as an antiseptic and wound healer since ancient ...
First in vivo evaluation of the mutagenic effect of Brazilian green propolis by comet assay and micronucleus test
(Pergamon-Elsevier B.V. Ltd, 2008-07-01)
Propolis is a hive product containing chiefly beeswax and plant-derived substances such as resin and volatile compounds. Propolis has been used in various parts of the world as an antiseptic and wound healer since ancient ...
Environmental Genotoxicity Assessment Using Micronucleus (and Nuclear Abnormalities) Test on Intertidal Mussel Perumytilus purpuratus: A Tool for Biomonitoring the Chilean Coast
(2021-01-01)
The release of pollutants is increasing along the coast of Chile, and the use of biomarkers in biomonitoring programs is essential to assess the early biological effects of marine contamination. The Micronucleus (MN) test ...
Evaluation of chemopreventive activity of glutamine by the comet and the micronucleus assay in mice's peripheral blood
(Elsevier B.V., 2009-07-01)
This research has evaluated the effects of enteral supplementation of glutamine in clastogens and genotoxic damages caused by the acute administration of cisplatin. For this. it was utilized Swiss mice distributed in eight ...
Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth
(Cevap-unespBotucatuBrasil, 2011)
Mutagenic and genotoxic effect of hydroxyurea
(2011-12-15)
The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the ...