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Genetic Alterations in Patients with Two Clinical Phenotypes of Multiple Sclerosis
(2020-01-01)
The etiology of multiple sclerosis (MS) is still not known, but the interaction of genetic, immunological, and environmental factors seem to be involved. This study aimed to investigate genetic alterations and the vitamin ...
Effect of lead on proliferation, oxidative stress and genotoxic damage of 3T3-L1 fibroblasts
(Oxford University Press, 2020-04)
Lead (Pb) is an environmental and industrial contaminant that still represents a public health problem. In this paper, we investigated the effect of Pb on proliferation, lipid peroxidation and the number of micronucleated ...
Colocalization of coilin and nucleolar proteins in Cajal body-like structures of micronucleated PtK2 cells
(Associação Brasileira de Divulgação Científica, 2004-07-01)
Cajal bodies (CB) are ubiquitous nuclear structures involved in the biogenesis of small nuclear ribonucleoproteins and show narrow association with the nucleolus. To identify possible relationships between CB and the ...
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma
(Wiley-Blackwell, 2002-01-01)
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay ...
Lentinula edodes (Shiitake) modulates chemically induced mutagenesis by enhancing pitting
(2013-08-01)
This study was undertaken to understand how Lentinula edodes modulates in vivo mutagenesis induced by alkylating agents in bone marrow and peripheral blood as described in our previous article. Male Swiss mice were pretreated ...
DNA damage in cytologically normal urothelial cells of patients with a history of urothelial cell carcinoma
(Wiley-Blackwell, 2002-01-01)
In order to determine if patients with a history of previous urothelial cell carcinoma (UCC) but with current normal urinary cytology have DNA damage in urothelial cells, the single-cell gel electrophoresis (comet) assay ...
Lentinula edodes (Shiitake) modulates chemically induced mutagenesis by enhancing pitting
(2013-08-01)
This study was undertaken to understand how Lentinula edodes modulates in vivo mutagenesis induced by alkylating agents in bone marrow and peripheral blood as described in our previous article. Male Swiss mice were pretreated ...