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Biological Properties and Analytical Methods for Micafungin: A Critical Review
(2020-01-01)
Micafungin is characterized as one of the most active available drugs for candidemia treatment; however, their use is also associated in prophylaxis protocols in cases of invasive fungal infections. The use of this drug ...
Breakthrough Invasive Candidiasis in Patients on Micafungin
(American Society for Microbiology, 2010-07)
For Candida species, a bimodal wild-type MIC distribution for echinocandins exists, but resistance to echinocandins is rare. We characterized isolates from patients with invasive candidiasis (IC) breaking through ≥3 doses ...
Multicenter study of anidulafungin and micafungin MIC distributions and epidemiological cutoff values for eight candida species and the CLSI M27-A3 broth microdilution method
(American Society for Microbiology, 2014)
Since epidemiological cutoff values (ECVs) using CLSI MICs from multiple laboratories are not available for Candida spp. and the echinocandins, we established ECVs for anidulafungin and micafungin on the basis of wild-type ...
Prophylaxis against fungal infections in solid organ and hematopoietic stem cells transplantation
(SOC CHILENA INFECTOLOGIA, 2012)
Invasive fungal infections are an important cause of morbidity and mortality in SOT and HSCT recipients. The main species involved are Candida spp. and Aspergillus spp, less frequently Cryptococcus spp., causal agents of ...
Prophylaxis against fungal infections in solid organ and hematopoietic stem cells transplantation Profilaxis antifúngica en niños y adultos sometidos a trasplante de órganos sólidos y de precursores hematopoyéticos
(2012)
Invasive fungal infections are an important cause of morbidity and mortality in SOT and HSCT recipients. The main species involved are Candida spp. and Aspergillus spp, less frequently Cryptococcus spp., causal agents of ...
Candida species: Current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options
(2013-01-01)
The incidence of fungal infections has increased significantly, so contributing to morbidity and mortality. This is caused by an increase in antimicrobial resistance and the restricted number of antifungal drugs, which ...
O papel do íon ferro nas infecções por Pythium insidiosum
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2014-01-30)
The oomycete Pythium insidiosum, classified in the kingdom Straminipila, is the agent of pythiosis, a chronic disease that can be hard to treat and life-threatening. The predisposing factors in mammals are unknown, but the ...