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Acquisition of stem associated-features on metastatic osteosarcoma cells and their functional effects on mesenchymal stem cells
(Elsevier Science, 2020-04)
Background: Osteosarcoma (OS) is the most frequent malignant bone tumor, affecting predominantly children and young adults. Metastases are a major clinical challenge in OS. In this context, 20% of OS patients are diagnosed ...
Hormone-independent mouse mammary adenocarcinomas with different metastatic potential exhibit different metabolic signatures
(MDPI AG, 2020)
The metabolic characteristics of metastatic and non-metastatic breast carcinomas remain poorly studied. In this work, untargeted Nuclear Magnetic Resonance (NMR) metabolomics was used to compare two medroxyprogesterone ...
Metastatic Cancer Stem Cells: New Molecular Targets for Cancer Therapy
(Bentham Science Publishers, 2011-11)
The cancer stem cell (CSC) hypothesis, predicts that a small subpopulation of cancer cells that possess "stem-like" characteristics, are responsible for initiating and maintaining cancer growth. According to the CSC model ...
Association of α v β 3 integrin expression with the metastatic potential and migratory and chemotactic ability of human osteosarcoma cells
(Springer, 2005-12)
INTRODUCTION: Expression of adhesion molecules such as alphavbeta3 integrin has been associated with the metastatic potential of tumor cells. The purpose of this study was to determine whether alphavbeta3 expression ...
Metastatic Niches and the Modulatory Contribution of Mesenchymal Stem Cells and Its Exosomes
(Molecular Diversity Preservation International, 2019-04)
Mesenchymal stem cells (MSCs) represent an interesting population due to their capacity to release a variety of cytokines, chemokines, and growth factors, and due to their motile nature and homing ability. MSCs can be ...
Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma
(2019-01-01)
Our lack of understanding of the immune microenvironment in canine osteosarcoma (cOSA) has limited the identification of potential immunotherapeutic targets. In particular, our ability to utilize readily available tissue ...
IMAGE-ANALYSIS - VIDEO SYSTEM ADEQUACY FOR THE ASSORTMENT OF NUCLEAR PHENOTYPES BASED ON CHROMATIN TEXTURE EVALUATION
(Japan Soc Histochemistry & CytochemistryKyotoJapão, 1994)
IMAGE-ANALYSIS OF FEULGEN-STAINED TRANSFORMED NIH 3T3 CELLS DIFFERING IN P21 EXPRESSION AND RAS-INDUCED METASTATIC ABILITY
(Sci Printers & Publ IncSt Louis, 1994)
Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors
(2020)
Abstract
Background
Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, ...
Restriction enzyme analysis of DNA methylation in "condensed" chromatin of Ha-ras-transformed NIH 3T3 cells
(Ios PressAmsterdamHolanda, 2000)