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A Density Functional Theory Study Of The Relationships Between Electronic Structure And Metabotropic Glutamate Receptor Subtype 5 Affinity Of 2- Amino- And 2-Halothiazole Derivatives
(2014)
We carried out an investigation and analysis of the relationships between the electronic structure and
the metabotropic glutamate receptor subtype 5 affinity for a series of 2-amino- and 2-halothiazole derivatives
using ...
Encephalitis associated to metabotropic glutamate receptor 5 (mGluR5) antibodies in cerebrospinal fluid
(Frontiers Media S.A., 2018)
Copyright © 2018 Guevara, Farias, Silva-Rosas, Alarcon, Abudinen, Espinoza, Caro, Angus-Leppan and de Grazia. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
The activation of metabotropic glutamate 5 receptors in the rat ventral tegmental area increases dopamine extracellular levels
(2017)
The mesocorticolimbic circuit projects to the prefrontal cortex, hippocampus, amygdala, and nucleus accumbens, among others, and it originates in the dopaminergic neurons of the ventral tegmental area (VTA). The VTA receives ...
Glutamate metabotropic receptors in the lateral hypothalamus/perifornical area reduce the CO 2 chemoreflex
(2019-02-01)
It has been shown that the lateral hypothalamus/perifornical area (LH/PFA) exerts an important role on arousal-state variations of the central chemoreflex, but the mechanisms that underlie LH/PFA chemoreception are poorly ...
Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor 1A-immunoreactivity in the hippocampus of juvenile rats
(Spandidos Publ. Ltd., 2016)
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by deficits in social communication and social interaction, and repetitive and stereotypical patterns of behavior. Previously, a ...
Metabotropic glutamate receptor (mGlu3R) splicing variants in aging and Alzheimer´s disease
(Wiley, 2019)
Subtype 3 metabotropic glutamate receptors (mGlu3R) promote several neuroprotective effects, especially in glial cells. We have previously demonstrated that mGlu3R activation in astrocytes promotes the non-amyloidogenic ...