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Complex networks: the key to systems biology
(Sociedade Brasileira de Genética, 2008)
Though introduced recently, complex networks research has grown steadily because of its potential to represent, characterize and model a wide range of intricate natural systems and phenomena. Because of the intrinsic ...
Network models in the study of metabolism
(Pontificia Universidad Católica de Valparaíso, 2009)
PhDSeeker: Pheromone-Directed Seeker for metabolic pathways
(Elsevier, 2020-12)
Manually finding relationship networks among compounds can be a hard and time-consuming task. However, this process is fundamental when looking for a metabolic pathway that explains how multiple compounds are related, to ...
Genome-scale reconstruction of the human astrocyte metabolic network
(Frontiers Research Foundation, 2017)
New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages
(Frontiers Media, 2020)
Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...
Weighting dissimilarities to detect communities in networks
(Royal Soc., 2015)
Many complex systems can be described as networks exhibiting inner organization as communities of nodes. The identification of communities is a key factor to understand community-based functionality. We propose a family ...
Combining graph and flux based structures to decipher phenotypic essential metabolites within metabolic networks
(PeerJ Inc., 2017)
Back ground. The emergence of functions in biological systems is a long-standing issue that can now be addressed at the cell level with the emergence of high throughput technologies for genome sequencing and phenotyping. ...
Spectral analysis and the dynamic response of complex networks
(American Physical SocCollege PkEUA, 2005)
Metabolic networks from (M, R) systems and autopoiesis perspective
(2002)
This paper is the first one of a series devoted to the analysis of metabolic networks. Its aim is to establish the theoretical framework for this analysis. Two different lines of research are considered: the one about ...