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Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration
(2021-01-01)
The exploitation of mesoporous silica nanoparticles (MSNs) as drug delivery systems has grown exponentially due to their remarkable tunable properties, such as high surface area, chemical and physical stability, high loading ...
Synthesis parameters for control of mesoporous silica nanoparticles (MSNs)
(Biointerface Research Applied Chemistry, 2016-10-15)
MSNs are excellent host matrices for molecules and biomolecules, making this material very promising for several nanotechnological applications in industry scale, chemical engineering, environmental, medicine and biology; ...
New insights towards mesoporous silica nanoparticles as a technological platform for chemotherapeutic drugs delivery
(2019-06-10)
Mesoporous silica nanoparticles (MSNs)displays interesting properties for biomedical applications such as high chemical stability, large surface area and tunable pores diameters and volumes, allowing the incorporation of ...
Metformin-loaded nanospheres-laden photocrosslinkable gelatin hydrogel for bone tissue engineering
(Elsevier B.V., 2021-04-01)
The aim of this investigation was to engineer metformin (MF)-loaded mesoporous silica nanospheres (MSNs)laden gelatin methacryloyl (GelMA) photocrosslinkable hydrogels and test their effects on the mechanical properties, ...
Highlights in Mesoporous Silica Nanoparticles as a Multifunctional Controlled Drug Delivery Nanoplatform for Infectious Diseases Treatment
(2020-10-01)
Infectious diseases are a major global concern being responsible for high morbidity and mortality mainly due to the development and enhancement of multidrug-resistant microorganisms exposing the fragility of medicines and ...
Influence of Protein Corona on the Transport of Molecules into Cells by Mesoporous Silica Nanoparticles
(Amer Chemical Soc, 2013-09-11)
Although there are several studies reporting the promising biological efficiency of mesoporous silica nanoparticles (loaded with antitumoral drugs) against cancer cells and tumors, there are no reports on the influence of ...
In Vivo Tracking of the Degradation of Mesoporous Silica through 89Zr Radio-Labeled Core–Shell Nanoparticles
(Wiley VCH Verlag, 2021-06)
While mesoporous silica nanoparticles (MSNs) are extensively studied as high-potential drug delivery platforms, the successful clinical translation of these nanocarriers strongly depends on their biodistribution, biodegradation, ...
Bifunctional mesoporous silica nanoparticles as cooperative catalysts for the Tsuji-Trost reaction: tuning the reactivity of silica nanoparticles
(Royal Society Chemistry - RSCCambridge, 2013-01)
Bifunctional mesoporous silica nanoparticles (MSNs) bearing Pd-complexes and additional basic siteswere prepared and tested as cooperative active catalysts in the Tsuji–Trost allylation of ethyl acetoacetate. Functionalization ...
Following in situ the degradation of mesoporous silica in biorelevant conditions: At last, a good comprehension of the structure influence
(American Chemical Society, 2020-02-20)
Mesoporous silica nanoparticles (MSNs) have seen a fast development as drug delivery carriers thanks to their tunable porosity and high loading capacity. The employ of MSNs in biomedical applications requires a good ...
Preparation and study of the antibacterial applications and oxidative stress induction of copper maleamate-functionalized mesoporous silica nanoparticles
(MDPI AG, 2019-01)
Mesoporous silica nanoparticles (MSNs) are an interesting class of nanomaterials with potential applications in different therapeutic areas and that have been extensively used as drug carriers in different fields of medicine. ...