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Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein
(American Society for Biochemistry and Molecular Biology, 2004)
Accurate characterization of the molecular mechanisms of the action of ligands is an extremely important issue for their appropriate research, pharmacological, and therapeutic uses. In view of this fact, the aim of the ...
Histaminergic H1 and H2 receptors located within the ventromedial hypothalamus regulate food and water intake in rats
(Elsevier, 2004)
The aim of the present study was to investigate the effect of the pharmacological blockade of histamine H1 and H2 receptors located within the ventromedial hypothalamus (VMH) on overnight food and water intake and on water ...
Central H1 and H2 receptor participation in the control of water and salt intake in rats
(Elsevier, 2005)
The aim of the present study was to evaluate the participation of brain H1 and H2 histaminergic receptors on water and salt intake induced by water deprivation (24 h), furosemide-induced sodium depletion and central ...