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Neuroanatomical and functional substrates of the medial prefrontal cortexSustratos neuroanatómicos y funcionales del córtex prefrontal medial
(Universidad Nacional de Córdoba, 2019)
Lateralização funcional do córtex pré-frontal medial na ansiedade em camundongos: avaliações molecular e psicofarmacológica
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2021-08-05)
The left and right medial prefrontal cortex (L & RmPFC) process emotional responses induced by stress-related stimuli, and LmPFC and RmPFC inhibition elicit anxiogenesis and anxiolysis, respectively. Here we sought to ...
Inhibition of the left medial prefrontal cortex (mPFC) prolongs the social defeat-induced anxiogenesis in mice: Attenuation by NMDA receptor blockade in the right mPFC
(2020-01-27)
Chemical inhibition and nitrergic stimulation of the left and right medial prefrontal cortex (L and RmPFC), respectively, provoke anxiety in mice. Moreover, LmPFC inhibition immediately followed by a single social defeat ...
Papel do córtex pré-frontal medial na ansiogênese induzida pelo estresse de derrota social em camundongos
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2018-10-18)
Recent findings have demonstrated that the medial prefrontal cortex (mPFC) has a lateralized role in the control of response to stressors, and the left hemisphere (LmPFC) would attenuate the anxiogenic responses elicited ...
Tonic modulation of anxiety-like behavior by corticotropin-releasing factor (CRF) type 1 receptor (CRF1) within the medial prefrontal cortex (mPFC) in male mice: Role of protein kinase A (PKA)
(Elsevier B.V., 2014-07-01)
The medial prefrontal cortex (mPFC) and the neuropeptide corticotropin-releasing factor (CRF) have recently been receiving more attention from those interested in the neurobiology of anxiety. Here, we investigated the CRF ...
Papel do complexo receptor glutamato/NMDA e óxido nítrico no córtex pré-frontal medial na ansiedade de camundongos expostos ao labirinto em cruz elevado
(Universidade Estadual Paulista (Unesp), 2021-12-13)
Medo e ansiedade são emoções decorrentes da resposta animal frente a estímulos ameaçadores ou perigosos, que resultam na exibição de reações de defesa. O estresse é um fator de risco para o desenvolvimento de diversos ...
Functional lateralization of the medial prefrontal cortex in the modulation of anxiety in mice: Left or right?
(2016-09-01)
It has been suggested that the left medial prefrontal cortex (LmPFC) has an inhibitory role in controlling the right mPFC (RmPFC), thereby reducing the deleterious effects of stressors on emotional states. Here, we ...
Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3
(Frontiers Media SA, 2018)
TRPM4 is a Ca2+-activated non-selective cationic channel that conducts monovalent cations. TRPM4 has been proposed to contribute to burst firing and sustained activity in several brain regions, however, the cellular and ...
Antidepressant-Like Effects of Medial Prefrontal Cortex Deep Brain Stimulation in Rats
(ELSEVIER SCIENCE INC, 2010)
Background: Subcallosal cingulate gyrus (SCG) deep brain stimulation (DBS) is being investigated as a treatment for major depression. We report on the effects of ventromedial prefrontal cortex (vmPFC) DBS in rats, focusing ...
Efeito do bloqueio dos receptores mineralocorticoides da região infra-límbica do córtex pré-frontal medial sobre a tolerância aos efeitos do midazolam em camundongos submetidos ao protocolo de teste e reteste no labirinto em cruz elevado
(Universidade Federal de São CarlosUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCFCâmpus São Carlos, 2017-05-25)
Several studies have shown that the previous experience (trial 1) to the elevated plus-maze
(EPM) increases the avoidance of the open arms and impairs the anxiolytic-like effect of
midazolam (MDZ), a benzodiazepine-GABAA ...