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Tumorogénesis y proteína mdm2
(Sociedad Médica de Santiago, 2000)
Amplification and protein expression of chromosome 12q13-15 genes in osteosarcomas of the jaws
(Pergamon-elsevier Science LtdOxfordInglaterra, 2001)
Alterations in PTEN, MDM2, TP53 and AR protein and gene expression are associated with canine prostate carcinogenesis
(2016-06-01)
The PTEN, AR, MDM2 and p53 protein network plays a central role in the development of many human cancers, thus eliciting the development of targeted cancer therapeutics. Dogs spontaneously develop tumours, and they are ...
Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase
(Nature Publishing Group, 2017-06)
Upon different types of stress, the gene encoding the mitosis-promoting phosphatase Cdc25C is transcriptionally repressed by p53, contributing to p53’s enforcement of a G2 cell cycle arrest. In addition, Cdc25C protein ...
Proliferating cell nuclear antigen (PCNA), p53 and MDM2 expression in Hodgkin's disease
(Associacao Paulista Medicina, 2007-03-01)
CONTEXT and OBJECTIVE: Tumor cells in Hodgkin's disease (HD) express cell proliferation markers that are evaluated according to the oncogenes involved or the expression of their proteins. Correlations between the protein ...
p53, Mdm2, and c-Myc overexpression is associated with a poor prognosis in aggressive non-Hodgkin's lymphomas
(Wiley-lissNew YorkEUA, 2001)
Avaliação da expressão proteica de PTEN, MDM2, P53 e AR em lesões proliferativas da próstata canina
(Universidade Estadual Paulista (Unesp), 2014-07-30)
The canine prostate may spontaneously develop prostatic proliferative lesions, associated with aging, inflammation and hormones, such as: benign prostatic hyperplasia (BPH), proliferative inflammatory atrophy (PIA) and ...
Investigation of the effect of MDM2 SNP309 and TP53 Arg72Pro polymorphisms on the age of onset of cutaneous melanoma
(Nature Publishing Group, 2012-05)
Melanoma accounts for the majority of deaths from skin cancer. Women tend to be diagnosed at a younger age and have better survival than men. A tumor-host interaction might be responsible for these gender-specific differences. ...