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Maximal electroshock-induced seizures are able to induce Homer1a mRNA expression but not pentylenetetrazole-induced seizures
(Elsevier B.V., 2015-03-01)
Objective: Homer1a is a protein that regulates metabotropic glutamate receptors involved in neural plasticity processes. Recently, we demonstrated that Homer1a mRNA is enhanced after pilocarpine-induced status epilepticus. ...
Transplantation of inhibitory precursor cells from medial ganglionic eminence produces distinct responses in two different models of acute seizure induction
(Academic Press Inc Elsevier Science, 2017)
Medial ganglionic eminence (MGE) is one of the sources of inhibitory interneurons during development. Following transplantation in postnatal developing brain, MGE cells can increase local inhibition suggesting a possible ...
Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners
(Bentham Science Publishers, 2014-12)
From a virtual screening campaign, a number of artificial and natural sweeteners were predicted as potential anticonvulsant agents with protective effects in the seizure animal model Maximal Electroshock Seizure (MES) test. ...
Anticonvulsant profile of 2-ethylthio-7-methyl-4-(4-methylphenyl) pyrazolo[1,5-a][1,3,5]triazine
(Universidade de Sao Paulo, 2014-03)
This work evaluates the central nervous effects in ICR strain mice of 2-ethylthio-7-methyl-4-(4-methylphenyl)pyrazolo[1,5-a][1,3,5]triazine (MH4b1), a compound obtained by an efficient one-step reaction of S,S-diethyl ...
Neurobehavioral effect of essential oil of Cymbopogon citratus in mice
(Elsevier Gmbh, Urban & Fischer Verlag, 2009-03-01)
Tea obtained from leaves of Cymbopogon citratus (DC) Stapf is used for its anxiolytic, hypnotic and anticonvulsant properties in Brazilian folk medicine. Essential oil (EO) from fresh leaves was obtained by hydrodistillation ...
Neurobehavioral effect of essential oil of Cymbopogon citratus in mice
(Elsevier Gmbh, Urban & Fischer Verlag, 2009-03-01)
Tea obtained from leaves of Cymbopogon citratus (DC) Stapf is used for its anxiolytic, hypnotic and anticonvulsant properties in Brazilian folk medicine. Essential oil (EO) from fresh leaves was obtained by hydrodistillation ...
Lipase Catalyzed Synthesis of Alkyl Phenylacetates with Anticonvulsant Activity
(Colegio de Farmacéuticos de la Provincia de Buenos Aires, 2020-06)
. A pesar del amplio espectro de medicamentos antiepilépticos disponibles, un tercio de los pacientes todavía sufren de epilepsia resistente a los mismos, lo que justifica la búsqueda continua de nuevas terapias. La actividad ...
Effects of seasonal variation on the central nervous system activity of Ocimum gratissimum L. essential oil
(Elsevier B.V., 2006-04-21)
Ocimum gratissimum L. (Lamiaceae) and other species of the same genus are used as medicines to treat central nervous system (CNS) diseases, commonly encountered in warm regions of the world. The chemical composition of ...