We present a mathematical model based on partial differential equations that is applied to understand tumor development and its response to chemotherapy. Our primary aim is to evaluate comparatively the efficacies of two ...

Dosage and frequency of treatment schedules are important for successful chemotherapy. However, in this work we argue that cell-kill response and tumoral growth should not be seen as separate and therefore are essential ...

Dosage and frequency of treatment schedules are important for successful chemotherapy. However, in this work we argue that cell-kill response and tumoral growth should not be seen as separate and therefore are essential ...

The field of mathematical oncology is exploding, with increasing efforts directed at laying down the foundation for the phenomena of cancer development, growth, metastases, and response to therapies. This work involves ...

We reported the final results obtained in a group of 30 patients with gastric cancer confined to the mucosa or submucosa (early gastric cancer) and in 29 cases with cancer infiltration up to the muscularis propria (intermediate ...

Chemotherapy rapidly proved its worth in different clinical cancer settings, begining with hematologic malignancies. Many pediatric and young adult tumors achieved complete remission with chemotherapy, but its use as ...

Immune checkpoint blockade (ICB) is becoming standard-of-care in many types of human malignancies, but patient selection is still imperfect. Tumor mutation burden (TMB) is being evaluated as a biomarker for ICB in clinical ...

The work is a documentary and bibliographic analysis with analytical nature and applied qualitative and quantitative approach that aimed at applying operational research methodology involving concepts of issues of health ...