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Using telomeric chromosomal aberrations to evaluate clastogen-induced genomic instability in mammalian cells
(Springer, 2020-12)
Telomeres, the specialized nucleoproteic complexes localized at the physical ends of linear eukaryotic chromosomes, play a fundamental role in maintaining chromosomal stability and integrity, being one of the leading ...
The methylating agent streptozotocin induces persistent telomere dysfunction in mammalian cells
(Elsevier Science, 2015-12)
We analyzed chromosomal aberrations involving telomeres in the progeny of mammalian cells exposed to the methylating agent and antineoplastic/diabetogenic drug streptozotocin (STZ), to test whether it induces long-term ...
The radiomimetic compound streptonigrin induces persistent telomere dysfunction in mammalian cells
(Elsevier Science, 2014)
Genomic organization of telomeric and subtelomeric sequences of Leishmania (Leishmania) amazonensis
(Pergamon-elsevier Science LtdOxfordInglaterra, 2005)
Telomere and Telomerase Biology
(Elsevier B.V., 2014-01-01)
Telomeres are the physical ends of eukaryotic linear chromosomes. Telomeres form special structures that cap chromosome ends to prevent degradation by nucleolytic attack and to distinguish chromosome termini from DNA ...
Effect of chemotherapeutic drugs on telomere length and telomerase activity
(Smart Science & Technology, 2016-12)
Telomeres are specialized nucleoproteic complexes localized at the ends of eukaryotic chromosomes, that maintain their stability and integrity. They protect chromosome ends from fusion and from being recognized as sites ...
The Leishmania amazonensis TRF ( TTAGGG repeat-binding factor) homologue binds and co-localizes with telomeres
(Biomed Central Ltd., 2010-05-07)
Background: Telomeres are specialized structures at the end of chromosomes essential for maintaining genome stability and cell viability. The importance of telomeric proteins for telomere maintenance has increased our ...
The Leishmania amazonensis TRF ( TTAGGG repeat-binding factor) homologue binds and co-localizes with telomeres
(Biomed Central Ltd., 2010-05-07)
Background: Telomeres are specialized structures at the end of chromosomes essential for maintaining genome stability and cell viability. The importance of telomeric proteins for telomere maintenance has increased our ...