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Pharmacokinetics and Biodistribution of Eriocitrin in Rats
(2021-02-17)
Eriocitrin plays a role in the reduction of oxidative stress and inflammation linked to the development of diabetes mellitus and atherosclerosis. We investigated the pharmacokinetics and distribution of eriocitrin metabolites ...
In vitro basal cytotoxicity assay applied to estimate acute oral systemic toxicity of grandisin and its major metabolite
(ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2011)
Preclinical investigations can start with preliminary in vitro studies before using animal models. Following this approach, the number of animals used in preclinical acute toxicity testing can be reduced. In this study, ...
Novel antimicrobial secondary metabolites from a Penicillium sp. isolated from Brazilian cerrado soil
(Pontificia Universidad Católica de Valparaíso, 2009)
Culture studies on the mycobiont isolated from Parmotrema reticulatum (Taylor) Choisy: metabolite production under different conditions
(Springer Heidelberg, 2009-08)
A strain of the lichen mycobiont isolated from Parmotrema reticulatum was cultured axenically on different media. The morphology, anatomy, growth of the colonies, and metabolite production were studied. The iisolated ...
Culture studies on the mycobiont isolated from Parmotrema reticulatum (Taylor) Choisy: Metabolite production under different conditions
(Springer Heidelberg, 2009-11)
A strain of the lichen mycobiont isolated from a thallus of Parmotrema reticulatum was cultured axenically on different media. The morphology, anatomy, growth of the colonies, and metabolite production were studied. The ...
Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: Preliminary results
(John Wiley & Sons LtdChichesterInglaterra, 2008)
Plant Metabolomics Using NMR Spectroscopy
(2019-01-01)
The major goal in plant metabolomics is to study complex extracts for the purposes of metabolic exploration and natural products discovery. To achieve this goal, plant metabolomics relies on accurate and selective acquisition ...
Metabolite‐based genome‐wide association study enables dissection of the flavonoid decoration pathway of wheat kernels
(Wiley Open AccessAssociation of Applied BiologistsSociety for Experimental BiologyBlackwell Publishing, 2020)
Application of in vitro Drug Metabolism Studies in Chemical Structure Optimization for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP)
(Frontiers Media Sa, 2019-04-24)
Currently no approved treatment exists for fibrodysplasia ossificans progressiva (FOP) patients, and disease progression results in severe restriction of joint function and premature mortality. LDN-193189 has been demonstrated ...