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Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to macrophage activation syndrome: Therapeutic implications
In light of the outbreak of the 2019 novel coronavirus disease (COVID-19), the international scientific community has joined forces to develop effective treatment strategies. The Angiotensin-Converting Enzyme (ACE) 2,
is ...
Macrophage Activation Syndrome Associated with Etanercept in a Child with Systemic Onset juvenile Idiopathic Arthritis
(ISRAEL MEDICAL ASSOC JOURNAL, 2009)
Acute pancreatitis in juvenile systemic lupus erythematosus: a manifestation of macrophage activation syndrome?
(SAGE PUBLICATIONS LTD, 2010)
Acute pancreatitis (AP) is a rare and life-threatening manifestation of juvenile systemic lupus erythematosus (JSLE). The objective of this study was to evaluate the prevalence and clinical features of AP in our JSLE ...
Macrophage Activation Syndrome in Juvenile Systemic Lupus Erythematosus A Multinational Multicenter Study of Thirty-Eight Patients
(Wiley-liss, 2009-11-01)
Objective. To describe the clinical and laboratory features of macrophage activation syndrome as a complication of juvenile systemic lupus erythematosus (SLE).Methods. Cases of juvenile SLE-associated macrophage activation ...
Macrophage Activation Syndrome in Juvenile Systemic Lupus Erythematosus A Multinational Multicenter Study of Thirty-Eight Patients
(Wiley-liss, 2009-11-01)
Objective. To describe the clinical and laboratory features of macrophage activation syndrome as a complication of juvenile systemic lupus erythematosus (SLE).Methods. Cases of juvenile SLE-associated macrophage activation ...
Macrophagic Activation Syndrome with Cytophagic Histiocytic Panniculitis in Pediatrics: Case ReportSíndrome de Activación Macrofágica con paniculitis histiocítica citofágica en pediatría: reporte de caso
(Intituto Tecnológico de Santo Domingo (INTEC), 2018)
Role of oxidized LDL-induced “trained macrophages” in the pathogenesis of COVID-19 and benefits of pioglitazone: A hypothesis
Background and aims: Older adults and people who have cardiovascular disorders (their common
pathogenetic mechanism is progressive atherosclerosis) are at higher risk for severe illness from COVID19 (coronavirus disease ...
Síndrome de ativação macrofágica em paciente com Lúpus eritematoso sistêmico juvenil
(2008-12-01)
Reactive haemophagocytosis or macrophage activation syndrome (MAS) is a complication of systemic inflammatory disorders, caused by expansion of T cells and haemophagocytic macrophages, with cytokine overproduction. It has ...
The multifaceted role of plasminogen in inflammation
A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the execution of the
inflammatory response. The zymogen/proenzyme plasminogen is converted to the serine protease plasmin, a ...