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Customized normothermic machine perfusion decreases ischemia–reperfusion injury compared with static cold storage in a porcine model of liver transplantation
(2023)
Background: Liver transplantation has been demonstrated to be the best treatment for several liver diseases, while grafts are limited. This has caused an increase in waiting lists, making it necessary to find ways to expand ...
Implementation and design of customized ex vivo machine perfusion. Analysis of its first results
(Wiley, 2021)
The lack of organs available for transplantation is a global problem. The high mortality rates on the waiting list and the high number of discarded livers are reasons to develop new tools in the preservation and transplantation ...
Development of a Novel Perfusable Solution for ex vivo Preservation: Towards Photosynthetic Oxygenation for Organ Transplantation
(Frontiers Media SA, 2021)
Oxygen is the key molecule for aerobic metabolism, but no animal cells can produce it, creating an extreme dependency on external supply. In contrast, microalgae are photosynthetic microorganisms, therefore, they are able ...
Hypothermic Machine Perfusion Versus Cold Storage in the Rescuing of Livers From Non-Heart-Beating Donor Rats
(Wiley, 2013-11)
The aim of this work was to compare the effi- ciency of cold storage (CS) and hypothermic machine perfusion (HMP) methods of preserving grafts excised from non-heart-beating donors that had suffered 45 minutes of warm ...
Randomized Trial of Machine Perfusion Versus Cold Storage in Recipients of Deceased Donor Kidney Transplants With High Incidence of Delayed Graft Function
(Lippincott Williams & Wilkins, 2017-06-01)
Background. This study compared the use of static cold storage versus continuous hypothermic machine perfusion in a cohort of kidney transplant recipients at high risk for delayed graft function (DGF). Methods. In this ...
Randomized Trial of Machine Perfusion Versus Cold Storage in Recipients of Deceased Donor Kidney Transplants With High Incidence of Delayed Graft Function
(Lippincott Williams & Wilkins, 2017-05-01)
Background. This study compared the use of static cold storage versus continuous hypothermic machine perfusion in a cohort of kidney transplant recipients at high risk for delayed graft function (DGF). Methods. In this ...
Eficacia de la máquina de perfusión hipotérmica comparada con almacenamiento en frio para la disminución del riesgo de desarrollar la función retardada del injerto en trasplante renal de donante cadaveEfficacy of the hypothermic perfusion machine compared to cold storage for the reduction of the risk of developing delayed graft function in cadave donor kidney transplantation
(Universidad Privada Norbert WienerPE, 2020)
The impact of hypothermic pulsatile machine perfusion versus static cold storage: A donor-matched paired analysis in a scenario of high incidence of delayed kidney graft function
(2020-01-01)
Background: Material/Methods: Results: Conclusions: The present study analyzed the impact of hypothermic pulsatile machine perfusion (MP) following a long period of static cold (SC) storage in the peculiar Brazilian scenario ...
The Novel N,N-bis-2-Hydroxyethyl-2-Aminoethanesulfonic Acid–Gluconate–Polyethylene Glycol–Hypothermic Machine Perfusion Solution Improves Static Cold Storage and Reduces Ischemia/Reperfusion Injury in Rat Liver Transplant
(John Wiley & Sons Inc, 2019-09)
Organ transplantation is the treatment of choice against terminal and irreversible organ failure. Optimal preservation of the graft is crucial to counteract cold ischemia effects. As we developed an N,N-bis-2-hydroxyethy ...