Using myeloid cell lines, it has been demonstrated that hyaluronan modulates transmembrane and soluble CD44H expression in immature (KG1a) but not mature (KG1) progenitors. Concomitantly, cell proliferation is decreased. ...

Ee recently read an article published in The Journal of Immunology by Enioutina et al. and found an experimental procedure we believe should be discussed.

As people get older, the homeostatic functions of many systems in the body like the immune system decline, which contributes to increase susceptibility to disease. The bone marrow of healthy individuals continually generates ...

The idea that within the bulk of leukemic cells there are immature progenitors which are intrinsically resistant to chemotherapy and able to repopulate the tumor after treatment is not recent. Nevertheless, the term leukemia ...

OBJECTIVES: Myeloid-derived suppressor cells contribute to the immunosuppressive microenvironment during tumor development and limit the efficacy of cancer immunotherapy. Identifying myeloid-derived suppressor cells and ...

An effective pathogen has the ability to evade the immune response. The strategies used to achieve this may be based on the direct action of virulence factors or on the induction of host factors. Myeloid-derived suppressor ...

Label-free methods for evaluating lectin-cell binding have been developed to determine the lectin-carbohydrate interactions in the context of cell-surface oligosaccharides. In the present study, mass loading and electrochemical ...