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Double hit lymphoma: from biology to therapeutic implications
(Taylor & Francis Online, 2016)
INTRODUCTION:
Diffuse large B-cell lymphoma (DLBCL) is a molecularly heterogeneous disease defined by different cellular origins and mechanisms of oncogenic activation. Approximately 10% of DLBCL cases harbor a MYC ...
Double hit lymphoma: from biology to therapeutic implications
(Taylor & Francis Online, 2016)
INTRODUCTION:
Diffuse large B-cell lymphoma (DLBCL) is a molecularly heterogeneous disease defined by different cellular origins and mechanisms of oncogenic activation. Approximately 10% of DLBCL cases harbor a MYC ...
Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2-and gamma-secretase inhibitors
(Ferrata Storti FoundationPaviaItália, 2010)
Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells
(American Physiological Society, 2014)
Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis
in muscle cells. Am J Physiol Endocrinol Metab 307: E209–E224,
2014. First published June 3, 2014; doi:10.1152/ajpendo.00045.2014.—
Elevating cytosolic ...
Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells
(2010)
Contraction-related stimuli regulate GLUT4 traffic in C2C12-
GLUT4myc skeletal muscle cells. Am J Physiol Endocrinol Metab
298: E1058 –E1071, 2010. First published February 16, 2010;
doi:10.1152/ajpendo.00773.2009.—Muscle ...
Papel de la policistina-1 en la regulación de la expresión de c-Myc y BIN1 en los cardiomiocitos
(Universidad de Chile, 2020)
La Policistina-1 (PC1) es un mecanosensor fundamental para la correcta contractilidad
cardiaca y su ausencia en los cardiomiocitos se relaciona con la disminución de los niveles
proteicos de los canales de calcio tipo-L ...
Molecular Effects Of The Phosphatidylinositol-3-kinase Inhibitor Nvp-bkm120 On T And B-cell Acute Lymphoblastic Leukaemia
(ELSEVIER SCI LTDOXFORD, 2015)
FGF2 Induces Breast Cancer Growth through Ligand-Independent Activation and Recruitment of ERα and PRB∆4 Isoform to MYC Regulatory Sequences
(John Wiley & Sons Inc, 2019-03)
Progression to hormone-independent growth leading to endocrine therapy resistance occurs in a high proportion of patients with estrogen receptor alpha (ERα) and progesterone receptors (PR) positive breast cancer. We and ...
AZT exerts its antitumoral effect by telomeric and non-telomeric effects in a mammary adenocarcinoma model
(Spandidos Publications, 2016-11)
Limitless replicative potential is one of the hallmarks of cancer that is mainly due to the activity of telomerase. This holoenzyme maintains telomere length, adding TTAGGG repetitions at the end of chromosomes in each ...
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters
(John Wiley & Sons Inc, 2014-11-12)
There is emerging interest in understanding the role of progesterone receptors (PRs) in breast cancer. The aim of this study was to investigate the proliferative effect of progestins and antiprogestins depending on the ...