In this contribution, a novel linear generalized disjunctive programming (LGDP) model is developed for the design of multiproduct batch plants optimizing both process variables and the structure of the plant through the ...

This work introduces a novel MILP formulation for reactive scheduling of multiproduct batch plants to optimally generate updated schedules due to the occurrence of unforeseen events. It can also be used to improve a ...

In this work a biotechnological multiproduct batch plant that manufactures four different recombinant proteins for human application is described in some detail. This batch plant design is then optimized with regards ...

A multipurpose/multiproduct plant has to deal with many combinations of tasks sequences and operation rates that lead to accumulation problems. These problems can be handled using storage tanks, but usually their location ...

New alternatives for the simultaneous design and planning of multiproduct batch plants in a multiperiod scenario are presented in this article. This formulation allows the flexible configuration of the plant in every time ...

A generalized disjunctive programming (GDP) model for the optimal design of multiproduct batch plants is presented. This general model manages the duplication of units in series to perform a given operation in the process, ...

The retrofit problem for multiproduct batch plants deals with the modification of the original structure of the plant to meet new production conditions such as the introduction of new products, a new supply pattern, etc. ...

The large number of studies addressing the scheduling problem in multiproduct batch plants with different units operating in parallel and out of phase at each stage highlights its importance in achieveing their efficient ...

In recent years, many companies have shifted from single-site production to more complex manufacturing environments involving multiple multiproduct facilities. At the operational level, the scheduling posed on each individual ...

This paper presents a general multiperiod optimization model, which simultaneously solves the design and planning decisions in multiproduct batch plants. Therefore, the trade-offs between both problems are taken into account ...