To validate the use of multicellular spheroids to predict the efficacy of herpes simplex thymidine kinase/ganciclovir (HSVtk/GCV) suicide gene therapy in the respective in vivo tumors, we established and characterized 15 ...

Parasiticides have been the most valuable weapons to combat parasites for almost half a century, constituting more than 50 % of veterinary pharmaceuticals and a good part of the products destined for human health. However, ...

Photodynamic therapy (PDT), a promising treatment option for cancer, involves the activation of a photosensitizer (PS) by local irradiation with visible light. Excitation of the PS leads to a series of photochemical reactions ...

Bacteria can relate to each other by forming multicellular aggregates known as biofilms. These associations of pathogenic microorganisms allow bacterial communities to resist the action of antimicrobials, stress and the ...

Las poblaciones bacterianas tienen la habilidad de adaptarse rápida y óptimamente a los cambios en los ambientes en los que existen. De esta manera, en ambientes propicios, con ausencia o baja incidencia de factores ...

High levels of arsenic present in the High Altitude Andean Lakes (HAALs) ecosystems selected arsenic-resistant microbial communities which are of novel interest to study adaptations mechanisms potentially useful in ...