Buscar
Mostrando ítems 1-10 de 16
Origin and progression of pregnancy-dependent mammary tumors induced by new mouse mammary tumor virus variants
(Springer, 2002-10)
In order to study mechanisms of progression of mouse mammary tumor virus (MMTV)-induced pregnancy-dependent mammary lesions, we removed and serially transplanted 17 small tumors detected in MMTV-infected pregnant females. ...
Critical role of dendritic cells in mouse mammary tumor virus in vivo infection
(American Society for Microbiology, 2007-04)
Mouse mammary tumor virus (MMTV) is a milk-transmitted betaretrovirus that causes mammary tumors in mice. Although mammary epithelial cells are the ultimate targets of MMTV, the virus utilizes components of the host immune ...
Detection of human mammary tumor virus proteins in human breast cancer cells
(Elsevier Science, 2010-01)
Mouse mammary tumor virus (MMTV) has been proven to induce mammary cancer in mice. MMTV-like env gene sequences have been detected in one-third of the human breast tumors studied. The whole proviral structure with 95% ...
Early increases in superantigen-specific Foxp3+ regulatory T cells during mouse mammary tumor virus infection
(American Society for Microbiology, 2008)
Mouse mammary tumor virus (MMTV) is a milk-borne betaretrovirus that has developed strategies to exploit and subvert the host immune system. Here, we show in a natural model of MMTV infection that the virus causes early ...
La depleción de las células T regulatorias aumenta el número de las células CD8 durante la infección con el virus del tumor mamario murinoRegulatory T cell depletion increases the number of CD8 cells during mouse mammary tumor virus infection
(Medicina (Buenos Aires), 2011-03)
El virus del tumor mamario murino (MMTV) es un retrovirus que se transmite durante la lactancia y que ha desarrollado estrategias para explotar y subvertir el sistema inmune. En un modelo de infección natural con MMTV hemos ...
The 5'-untranslated region of the mouse mammary tumor virus mRNA exhibits cap-independent translation initiation
(OXFORD UNIV PRESS, 2010)
In this study, we demonstrate the identification of an internal ribosome entry site (IRES) within the 5'-untranslated region (5'-UTR) of the mouse mammary tumor virus (MMTV). The 5'-UTR of the full-length mRNA derived from ...
NetH2pan: A computational tool to guide MHC peptide prediction on murine tumors
(American Association for Cancer Research, 2018-06)
With the advancement of personalized cancer immunotherapies, new tools are needed to identify tumor antigens and evaluate T-cell responses in model systems, specifically those that exhibit clinically relevant tumor ...
Chromatin remodeling and control of cell proliferation by progestins via cross talk of progesterone receptor with the estrogen receptors and kinase signaling pathways
(Wiley, 2006-12-11)
Transcription from the mouse mammary tumor virus (MMTV) promoter can be induced by glucocorticoids or progestins. Progesterone treatment of cultured cells carrying an integrated single copy of an MMTV transgene leads to ...
Neonatal infection with a milk-borne virus is independent of β7 integrin- and L-selectin-expressing lymphocytes
(Wiley VCH Verlag, 2002-04)
Mouse mammary tumor virus (MMTV) is acquired by neonates through milk and first infects lymphocytes in Peyer’s patches. We show here that newborn mice lacking 7 integrin or Lselectin were infected with MMTV at wild-type ...
Characterization of viral particles isolated from primary cultures of human breast cancer cells
(American Association for Cancer Research, 2007-09)
The association of human breast cancer with sequences similar to the mouse mammary tumor virus (MMTV) has been shown, but convincing evidence for the presence of viral particles in breast tumors has been lacking. We have ...