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Dehydroleucodine inhibits mitotic clonal expansion during adipogenesis through cell cycle arrest
(John Wiley & Sons Ltd, 2018-08)
Aberrant levels of preadipocyte differentiation, triggered by adipocyte hyperplasia and hypertrophy, results in the obesogenic phenotype. Obesity is a risk factor for several metabolic disorders. In this paper, dehydroleucodine ...
Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection
(Public Library of Science, 2013-10)
Deltaretroviruses such as human T-lymphotropic virus type 1 (HTLV-1) and bovine leukemia virus (BLV) induce a persistent infection that remains generally asymptomatic but can also lead to leukemia or lymphoma. These viruses ...
Tratamiento con imatinib y el farmacogenotipo CYP3A4 en relación con la expansión clonal Ph(+) en leucemia mieloide crónica (LMC).
(2012-11-26)
Introducción: imatinib es un inhibidor de la tirosina-kinasa BCR-ABL que revolucionó el tratamiento de pacientes con
leucemia mieloide crónica (LMC) positivos para cromosoma Philadelphia (Ph+). Este medicamento se ...
Antiadipogenic effect of carnosic acid, a natural compound present in Rosmarinus officinalis, is exerted through the C/EBPs and PPARγ pathways at the onset of the differentiation program
(Elsevier Science, 2013-06)
Background Obesity is a serious health problem all over the world, and inhibition of adipogenesis constitutes one of the therapeutic strategies for its treatment. Carnosic acid (CA), the main bioactive compound of Rosmarinus ...
Tratamiento con imatinib y el farmacogenotipo CYP3A4 en relación con laexpansión clonal Ph(+) en leucemia mieloide crónica (LMC)Imatinib treatment and pharmacogenotype CYP3A4 in relation with the clonal expansion Ph(+) in chronic myeloidleukemia (CML)
(Universidad del ValleGenética Regeneración y CáncerCali, Colombia, 2021)
N-acetylcysteine inhibits lipid accumulation in mouse embryonic adipocytes
(Elsevier, 2016-10)
Oxidative stress plays critical roles in the pathogenesis of diabetes, hypertension, and atherosclerosis; some authors reported that fat accumulation correlates to systemic oxidative stress in human and mice, but cellular ...
Lead enhancement of 3T3-L1 fibroblasts differentiation to adipocytes involves ERK, C/EBPβ and PPARγ activation
(Springer, 2018-01)
Lead (Pb) is an environmental and industrial contaminant that still represents a public health problem. Elevated Pb exposure has been inversely correlated with femoral bone density and associated with osteoporosis. In the ...
Effect of hexavalent chromium on proliferation and differentiation to adipocytes of 3T3-L1 fibroblasts
(Elsevier, 2014-02)
Heavy metals contamination has become an important risk factor for public health and the environment. Chromium is a frequent industrial contaminant and is also used in orthopaedic joint replacements made from cobalt–chro ...