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Simultaneous determination of rosiglitazone and its metabolites in rat liver microsomal fraction using hollow-fiber liquid-phase microextraction for sample preparation
(WILEY-V C H VERLAG GMBH, 2010)
A three-phase hollow-fiber liquid-phase microextraction method for the analysis of rosiglitazone and its metabolites N-desmethyl rosiglitazone and p-hydroxy rosiglitazone in microsomal preparations is described for the ...
AMP hydrolysis in soluble and microsomal rat cardiac cell fractions: kinetic characterization and molecular identification of 5 `-nucleotidase
(PORTLAND PRESS LTD, 2008)
The present study describes the enzymatic properties and molecular identification of 5`-nucleotidase in soluble and microsomal fractions from rat cardiac ventricles. Using AMP as a substrate, the results showed that the ...
ACCUMULATION OF A HOST MICROSOMAL FRACTION PROTEIN IN VIRUS-INFECTED CUCUMBER AND TOMATO
(Gauthier-villarsMontrougeFrança, 1995)
Oxidation of ethanol to acetaldehyde and free radicals by rat testicular microsomes
(Springer, 2005-01)
A large number of epidemiological studies evidencing that excessive alcohol consumption is associated with impaired testosterone production and testicular atrophy are available in the literature. One hypothesis to explain ...
Evidence of in vitro glucuronidation and enzymatic transformation of paralytic shellfish toxins by healthy human liver microsomes fraction
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
In vitro characterization of rosiglitazone metabolites and determination of the kinetic parameters employing rat liver microsomal fraction
(SPRINGER FRANCE, 2011)
Rosiglitazone (RSG), a thiazolidinedione antidiabetic drug, is metabolized by CYP450 enzymes into two main metabolites: N-desmethyl rosiglitazone (N-Dm-R) and rho-hydroxy rosiglitazone (rho-OH-R). In humans, CYP2C8 appears ...
Aging promotes a different phosphatidic acid utilization in cytosolic and microsomal fractions from brain and liver
(Pergamon-Elsevier Science Ltd, 2001-08)
Among the morphological and biochemical changes taking place in the membranes of aged tissues, we reported in previous studies on alterations in phospholipid synthesis and phospholipid-specific fatty acid composition. ...
Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state: Relation to lipid peroxidation
(1985)
The effect of thyroid hormone treatment on hepatic microsomal functions related to NADPH-dependent electron transfer reactions was studied in rats given 0.1 mg T3/ kg BW for 1, 2, 3, and 7 consecutive days. This treatment ...
Chiral HPLC analysis of venlafaxine metabolites in rat liver microsomal preparations after LPME extraction and application to an in vitro biotransformation study
(SPRINGER HEIDELBERG, 2010)
A three-phase LPME (liquid-phase microextraction) method for the enantioselective analysis of venlafaxine (VF) metabolites (O-desmethylvenlafaxine (ODV) and N-desmethylvenlafaxine (NDV) in microsomal preparations is described ...
Comparative subcellular distribution of apyrase from animal and plant sources. Characterization of microsomal apyrase
(1989)
1. 1. Apyrase (ATP: diphosphohydrolase) has been found in the microsomal fraction of rat salivary gland, mammary gland and uterus. 2. 2. This enzyme, already described in plant tissues, is mainly present as a soluble ...