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Direct Coupling of Dispersive Extractions with Magnetic Particles to Mass Spectrometry via Microfluidic Open Interface
(American Chemical Society, 2019-04)
Microextraction coupled to mass spectrometry (MS) has great potential in analytical chemistry laboratories operating in a variety of fields. Indeed, microextraction methods directly coupled to MS can be of large value given ...
Rapid determination of tacrolimus and sirolimus in whole human blood by direct coupling of solid-phase microextraction to mass spectrometry via microfluidic open interface
(Elsevier Science, 2021-02)
Immunosuppressive drugs are administered to decrease immune system activity (e.g. of patients undergoing solid organ transplant). Concentrations of immunosuppressive drugs (ISDs) in circulating blood must be closely monitored ...
Solid phase microextraction coupled to mass spectrometry: Via a microfluidic open interface for rapid therapeutic drug monitoring
(Royal Society of Chemistry, 2019-06)
Tranexamic acid (TXA) is an antifibrinolytic used during cardiac surgery that presents high inter-patient variability. High plasma concentrations have been associated with post-operative seizures. Due to the difficulties ...
Gravity driven flow for the precise control of hydrodynamic focusing
(Universidad Nacional de Córdoba, 2019)
Hydrodynamic focusing is a key operation in microfluidics, withapplications that range from cell sorting and counting to mixing and reactions.For most of these operations, both stability and precise handling of thefocused ...
Brushes of semiflexible polymers in equilibrium and under flow in a super-hydrophobic regime
(Royal Society of Chemistry, 2015-06)
We performed molecular dynamics simulations to study the equilibrium and flow properties of a liquid ina nano-channel with confining surfaces coated with a layer of grafted semiflexible polymers. Thecoverage spans a wide ...
Production of hyaluronic acid (HA) nanoparticles by a continuous process inside microchannels: Effects of non-solvents, organic phase flow rate, and HA concentration
(Pergamon-elsevier Science LtdOxfordInglaterra, 2012)
Microheater for microfluidic systems
(Universidad de los AndesIngeniería ElectrónicaFacultad de IngenieríaDepartamento de Ingeniería Eléctrica y Electrónica, 2022-12-13)
Microfluidics devices have been a tool to develop low-cost alternatives for research in pharmaceutical, medical, and biomedical fields. This is because they allow miniaturizing the process and thus reduce the volumes of ...
Formación de microcápsulas para envío de fármacos a partir de emulsiones usando dispositivos microfluídicos
(Universidad Michoacana de San Nicolás de Hidalgo, 2018-08)
In this thesis, the study and development of different kind of microcapsules is presented. Microcapsules were formed using the method of microfluidics. As the structural elements to form the microcapsules, the following ...
Innovative biofabrication: integrating microfluidics, nanotechnology, and multiphysics simulations in tissue engineering
(Universidad de los AndesMaestría en Ingeniería BiomédicaFacultad de IngenieríaDepartamento de Ingeniería Biomédica, 2023-05-29)
The escalating cost of medicine production and ethical concerns surrounding animal testing have driven the need for alternative approaches in drug development. Tissue engineering, organ-on-a-chip technology, bioprinting, ...
Modelo numerico eficiente para flujo electrocinetico en sistemas microfluidicos con geometrias complejas
(Asociación Argentina de Mecánica Computacional, 2007-12)
Microfluidic devices like those used in chemical and biomedical applications basically consist of different networks of microchannels that interconnect chambers and reservoirs. The transport of fluids throughout the ...