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From yeast killer toxins to antibiobodies and beyond
(Wiley-Blackwell, 2008-11-01)
Antibiobodies are paradigmatic of yeast killer toxin (KT)-like antibodies (KAbs) mimicking the antimicrobial activity of KTs in the frame of the yeast killer phenomenon. Polyclonal, monoclonal and recombinant anti-idiotypic ...
Stable Colloidal Copper Nanoparticles Functionalized with Siloxane Groups and Their Microbicidal Activity
(Springer, 2018-12)
The emergence and spread of pathogenic microbes with resistance to multiple antibiotics necessitates the development of new broad-spectrum microbicides. Metal nanoparticles are one such microbicide and they have been ...
Microbicidal activity of N-chlorotaurine in combination with hydrogen peroxide
(2017-12-01)
N-chlorotaurine (NCT) and hydrogen peroxide are powerful endogenous antiseptics. In vivo, the reaction between hydrogen peroxide and metal ions leads to the formation of free hydroxyl radicals, which have an increased ...
ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: Optimal candidate for microbicide combinations
(Oxford University Press, 2006-09)
The acidic vaginal milieu is presumed to inactivate pathogens but is neutralized by semen. This notion fostered the development of acid-buffering products, such as ACIDFORM (developed by Program for Topical Prevention of ...
Frequency, patterns, and preferences of lubricant use during anal intercourse within male sexual partnerships in Lima, Peru: Implications for a rectal microbicide HIV prevention intervention
(Taylor and Francis, 2013)
Understanding current practices of lubricant use during anal intercourse can help to assess the contexts for the introduction of topical rectal microbicides as an HIV prevention tool for men who have sex with men (MSM). ...
Vaginal safety after use of a bioadhesive, acid-buffering, microbicidal contraceptive gel (ACIDFORM) and a 2% nonoxynol-9 product
(Elsevier Science IncNew YorkEUA, 2006)
Delivery of microbicides to the vagina: difficulties reported with the use of three devices, adherence to use and preferences
(Elsevier Science IncNew YorkEUA, 2007)