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Estudos estruturais e ensaios biológicos de proteínas codificadas por genes de micro-exon (MEG) de Schistosoma mansoni
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, 2014-09-05)
Schistosoma mansoni is the causative agent of Schistosomiasis, reaching 249 million people in 78 countries. It is believed that this infection is successful due to modulation of the host immune system through proteins ...
Circulating microRNAs in Huntington's disease: Emerging mediators in metabolic impairment
(Academic Press, 2016)
Gene structure and splicing in schistosomes
(ElsevierAmsterdam, 2011-08)
Schistosomes are blood dwelling platyhelminths with a complex life cycle and persist in the definitive host during decades, indicating that they are very successful parasites. The challenge of infecting two hosts from ...
Exploring the Schistosoma mansoni adult male transcriptome using RNA-seq
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2012)
Schistosoma mansoni is one of the agents of schistosomiasis, a chronic and debilitating disease. Here we, present a transcriptome-wide characterization of adult S. mansoni males by high-throughput RNA-sequencing. We obtained ...
Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts
(COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2010)
Schistosoma mansoni is a well-adapted blood-dwelling parasitic helminth, persisting for decades in its human host despite being continually exposed to potential immune attack. Here, we describe in detail micro-exon genes ...
Folding factors and partners for the intrinsically disordered protein micro-exon gene 14 (MEG-14)
(Cell PressSaint Louis, 2013-06)
The micro-exon genes (MEG) of Schistosoma mansoni, a parasite responsible for the second most widely spread tropical disease, code for small secreted proteins with sequences unique to the Schistosoma genera. Bioinformatics ...
Microdissecção e captura a laser na investigação do gene TP53 em tecidos incluídos em parafina
(2007-02-01)
Background: Laser-capture micro-dissection (LCM) is a recently developed procedure that provides single cells or specific cell groups for molecular analysis. Currently, there are few LCM systems in Brazil, in such a way ...
Microdissecção e captura a laser na investigação do gene TP53 em tecidos incluídos em parafina
(Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2007-02-01)
INTRODUÇÃO: Microdissecção e captura a laser (MCL) é uma técnica de desenvolvimento recente que permite a coleta de células individuais ou pequeno conjunto de células para análise molecular. Atualmente, no Brasil, há raros ...