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STAT3 inhibition by STA21 increases cell surface expression of MICB and the release of soluble MICB by gastric adenocarcinoma cells
(Elsevier, 2017)
NKG2D is an activating receptor expressed on NK cells that binds to a variety of ligands, including MICA and MICB. These cell surface glycoproteins are overexpressed under cellular transformation, thus playing an important ...
In vitro effects of antimicrobial agents on planktonic and biofilm forms of staphylococcus saprophyticusisolated from patients with urinary tract infections
(2019-01-01)
Bacterial biofilms play an important role in urinary tract infections (UTIs), being responsible for persistent infections that lead to recurrences and relapses. Staphylococcus saprophyticus is one of the main etiological ...
Evaluación de la expresión génica de mica, micb, adam10, adam17 y mmp14 en lesiones intraepiteliales cervicales en pacientes residentes en Bogotá
(2014)
NKG2D es un receptor activador expresado en las células naturales asesinas involucrado en la eliminación de células transformadas y/o infectadas por virus. Dentro de los ligandos descritos para este receptor están MICA ...
Clinical significance of tumor expression of major histocompatibility complex class I-related chains A and B (MICA/B) in gastric cancer patients
(2016)
Gastric cancer (GC) is the third most common cause of cancer death worldwide. Natural killer cells play an important role in the immune defense against transformed cells. They express the activating receptor NKG2D, whose ...
MHC Variants Associated With Symptomatic Versus Asymptomatic SARS-CoV-2 Infection in Highly Exposed Individuals
(2021-09-28)
Despite the high number of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who develop coronavirus disease 2019 (COVID-19) symptoms worldwide, many exposed individuals remain asymptomatic ...
Estudio de moléculas chaperonas humanas involucradas en la expresión en superficie de proteínas MICA y MICB en células de melanoma
(Universidad de Chile, 2009)
En Chile, la tasa de mortalidad por enfermedades oncológicas ha ido aumentando año a año, siendo las cifras cada vez más preocupantes. Es por eso, que cualquier aporte que pueda hacerse en este ámbito puede ser fundamental ...