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Surviving despite reduce MHC variation: selection patterns and genetic variation of the endangered Huillín (Lontra provocax)
(Springer Science and Business Media Deutschland GmbH, 2021)
© 2021, Mammal Research Institute, Polish Academy of Sciences, Bialowieza, Poland.The major histocompatibility complex (MHC) is a highly polymorphic gene group that mediates the vertebrate immune response through antigen ...
Colonizing the world in spite of reduced MHC variation
(Wiley Blackwell Publishing, Inc, 2012-07)
The major histocompatibility complex (MHC), which harbours the most polymorphic vertebrate genes, plays a critical role in the host-pathogen coevolutionary arms race. However, the extent to which MHC diversity determines ...
Interpopulation differences in parasite load and variable selective pressures on MHC genes in Ctenomys talarum
(Alliance Communications Group Division Allen Press, 2014-08)
We explore potential geographic variation in the pathogen-mediated selective pressures acting on Major Histocompatibility Complex (MHC) loci in the subterranean rodent Ctenomys talarum, evaluating the impact of differences ...
Identification of the cognate peptide-MHC target of T cell receptors using molecular modeling and force field scoring
(Pergamon-Elsevier Science Ltd, 2018-02)
Interactions of T cell receptors (TCR) to peptides in complex with MHC (p:MHC) are key features that mediate cellular immune responses. While MHC binding is required for a peptide to be presented to T cells, not all MHC ...
MHC variation, multiple simultaneous infections and physiological condition in the subterranean rodent Ctenomys talarum
(Elsevier Science, 2011-07)
Parasites and pathogens can play a significant role in shaping the genetic diversity of host populations, particularly at genes associated with host immune response. To explore this relationship in a natural population of ...
MHC-B variation in maternal and paternal synthetic lines of the Argentinian Campero INTA chicken
(Elsevier, 2021-05)
The Campero-INTA chicken of Argentina was developed to provide a robust bird that can survive under Argentinian pasture conditions with no significant additional nutrition, producing a source of animal protein for small ...
Utrophin, MHC and M1/M2 macrophages in GRMD dogsUtrofina, MHC e macrófagos M1 e M2 em cães DMGR
(2020-01-01)
Muscular dystrophies are hereditary diseases that lead to progressive degeneration of the skeletal musculature. Golden Retriever dogs are used as animal models because they show a hereditary muscle disease similar to ...
Análisis y revisión de la variación del MHC-B en pollos. Síntesis del trabajo en líneas sintéticas INTAAnalysis and review of the variation of MHC-B in chickens. Synthesis of work on INTA synthetic linesAnálise e revisão da variação do MHC-B em frango. Síntese de trabalho em linhas sintéticas INTA
(Facultad de Ciencias Veterinarias. Universidad Nacional de La Pampa, 2022)