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Evidence of absence of Trypanosoma cruzi kinetoplast DNA methylation by restriction endonuclease analysis
(1991)
Evidence of absence of Trypanosoma cruzi kinetoplast DNA methylation by restriction endonuclease analysis. International Journal for Parasitology bd21: 863-866. Eight kinetoplast DNA samples from very different T. cruzi ...
In vitro methylation of the elongation factor EF-Tu from Escherichia coli
(1985)
The in vitro methylation of the elongation factor EF-Tu from Escherichia coli was investigated. The methylation of newly synthesized EF-Tu was obtained using lambda rifd 18 DNA as template and S-adenosyl [methyl-3H]methionine ...
DNA methylation analysis of tumor suppressor genes in monoclonal gammopathy of undetermined significance
(Springer, 2010-02)
Aberrant DNA methylation is considered an important epigenetic mechanism for gene inactivation. Monoclonal gammopathy of undetermined significance (MGUS) is believed to be a precursor of multiple myeloma (MM). We have ...
Screening methylation of DNA repair genes in the oral mucosa of chronic smokers
(2018-08-01)
Objective: The aim of this study was to evaluate the epigenetic changes in the process of oral carcinogenesis by screening the methylation of repair genes in chronic smokers. Design: Two groups were formed: Group 1: 16 ...
Search for methylation-sensitive amplification polymorphisms in mutant figs
(2013-07-08)
Fig (Ficus carica) breeding programs that use conventional approaches to develop new cultivars are rare, owing to limited genetic variability and the difficulty in obtaining plants via gamete fusion. Cytosine methylation ...
Search for methylation-sensitive amplification polymorphisms in mutant figs
(2013-07-08)
Fig (Ficus carica) breeding programs that use conventional approaches to develop new cultivars are rare, owing to limited genetic variability and the difficulty in obtaining plants via gamete fusion. Cytosine methylation ...
DNA methylation analysis of the tumor suppressor gene CDKN2B in Brazilian leukemia patients
(Sociedade Brasileira de Genética, 2008)
The aim of this work was to evaluate the methylation profile of the p15 (CDKN2B) gene in Brazilian patients with leukemia and to correlate the CDKN2B gene expression with the percentage of methylated CpG dinucleotides in ...
Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma
(Faculdade de Medicina / USP, 2011)
OBJECTIVES: 1) To correlate the methylation status of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter to its gene and protein expression levels in glioblastoma and 2) to determine the most reliable method for ...
The spectrum of tuberculosis described as differential DNA methylation patterns in alveolar macrophages and alveolar T cells
(BioMed Central, 2022)
Background: Host innate immune cells have been identified as key players in the early eradication of Mycobacterium tuberculosis and in the maintenance of an anti-mycobacterial immune memory, which we and others have shown ...