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Methacycline: A Review of Analytical Methods
(Bentham Science Publ Ltd, 2012-02-01)
Methacycline is a broad spectrum, semisynthetic antibiotic prepared from oxytetracycline. Its antibacterial spectrum is as same as that of tetracycline, but its efficacy is superior to that of oxytetracycline and tetracycline. ...
Methacycline: A Review of Analytical Methods
(Bentham Science Publ Ltd, 2012-02-01)
Methacycline is a broad spectrum, semisynthetic antibiotic prepared from oxytetracycline. Its antibacterial spectrum is as same as that of tetracycline, but its efficacy is superior to that of oxytetracycline and tetracycline. ...
Methacycline: A Review of Analytical Methods
(Bentham Science Publ Ltd, 2014)
In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2
(Frontiers Media S.A., 2019-08-06)
Malaria is among the leading causes of death worldwide. The emergence of Plasmodium falciparum resistant strains with reduced sensitivity to the first line combination therapy and suboptimal responses to insecticides used ...
Tetracycline Derivatives Inhibit Plasmodial Cysteine Protease Falcipain-2 through Binding to a Distal Allosteric Site
(2022-01-10)
Allosteric inhibitors regulate enzyme activity from remote and usually specific pockets. As they promise an avenue for less toxic and safer drugs, the identification and characterization of allosteric inhibitors has gained ...
Discovery of novel falcipain 2 inhibitors by in silico guided drug repositioning
(University of Dundee, 2019)
Malaria is a life-threatening condition that continues being one of global leading causes of death worldwide, being themain cause of death globally in the 5-14 year-old population. The disease is caused by parasites from ...
In silico-guided drug repurposing: identification of non-competitive inhibitors of Trypanosoma cruzi and Plasmodium falciparum cysteine proteases
(Fundación Revista Medicina, 2020)
Abstract/Resumen: Trypanosoma cruzi and Plasmodium falciparum are the etiologic agents of Chagas disease and Malaria, respectively. Cysteine proteases play key roles in the pathogenesis and survival of these parasites, ...
Desenvolvimento e avaliação biofarmacêutica de supositórios de doxiciclina hiclato para uso veterinário
(Universidade Federal de Santa MariaBrasilAnálises Clínicas e ToxicológicasUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2018-08-17)
Veterinary drug therapy can be quite laborious especially when performed in the home environment. Usually the animal drug treatment is done by the oral or injectable route, but the rectal route can be an alternative. The ...