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Similar structures but different mechanisms: Prediction of FABPs-membrane interaction by electrostatic calculation
(Elsevier Science, 2012-07)
The role of fatty acid binding proteins as intracellular fatty acid transporters may require their direct interaction with membranes. In this way different mechanisms have been previously characterized through experimental ...
Electrostatic Interactions Are Not Sufficient to Account for Chitosan Bioactivity
(AMER CHEMICAL SOC, 2010)
Recent studies involving chitosan interacting with phospholipid monolayers that mimic cell membranes have brought molecular-level evidence for some of the physiological actions of chitosan, as in removing a protein from ...
Strategies for exploring electrostatic and nonelectrostatic contributions to the interaction of helical antimicrobial peptides with model membranes
(2016-01-01)
Linear antimicrobial peptides, short sequences up to 50 amino acids, rich in basic and hydrophobic residues, are able to form an amphipathic helix when adsorbed onto lipid membranes. Thanks to these characteristics they ...
Integral Representation of Electrostatic Interactions inside a Lipid Membrane
(2020-09-01)
Interactions between charges and dipoles inside a lipid membrane are partially screened. The screening arises both from the polarization of water and from the structure of the electric double layer formed by the salt ions ...
Relevance of the protein macrodipole in the membrane-binding process. Interactions of fatty-acid binding proteins with cationic lipid membranes
(Public Library of Science, 2018-03)
The fatty acid-binding proteins L-BABP and Rep1-NCXSQ bind to anionic lipid membranes by electrostatic interactions. According to Molecular Dynamics (MD) simulations, the interaction of the protein macrodipole with the ...
Conserved charged amino acids are key determinants for fatty acid binding proteins (FABPs)-membrane interactions. A multi-methodological computational approach
(Taylor & Francis, 2018-03)
Based on the analysis of the mechanism of ligand transfer to membranes employing in vitro methods, Fatty Acid Binding Protein (FABP) family has been divided in two subgroups: collisional and diffusional FABPs. Although the ...