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Comparison of Bidirectional Lamivudine and Zidovudine Transport Using MDCK, MDCK-MDR1, and Caco-2 Cell Monolayers
(JOHN WILEY & SONS INC, 2009)
Bidirectional transport studies were conducted using Caco-2, MDCK, and MDCK-MDR1 to determine P-gp influences in lamivudine and zidovudine permeability and evaluate if zidovudine permeability changes with the increase of ...
A simple epithelial cell line (MDCK) shows heterogeneity of desmoglein isoforms, one resembling pemphigus vulgaris antigen
(Journal Of Cell Science, 2018)
Modulation of the epithelial barrier by dexamethasone and prolactin in cultured Madin-Darby canine kidney (MDCK) cells
(Academic Press Ltd Elsevier Science LtdLondonInglaterra, 2006)
Identification of a Novel Mono-Leucine Basolateral Sorting Motif Within the Cytoplasmic Domain of Amphiregulin
(WILEY, 2011)
Epithelial cells establish apical and basolateral (BL) membranes with distinct protein and lipid compositions. To achieve this spatial asymmetry, the cell utilizes a variety of mechanisms for differential sorting, delivery ...
Impairment of the cell-to-matrix adhesion and cytotoxicity induced by Bothrops moojeni snake venom in cultured renal tubular epithelia
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2002)
Characterization of thiol-, aspartyl-, and thiol-metallo-peptidase activities in Madin-Darby canine kidney cells
(Wiley-Blackwell, 2000-01-01)
We combined fluorogenic substrates or internally quenched fluorescent peptides with specific inhibitors in the pH profile of proleolytic activity experiments in order to detect proteolytic activities in lysates of MDCK ...
Avaliação da nefrotoxicidade causada pela anfotericina B utilizando linhagens celulares LLC-PK1 e MDCK.2
(Universidade Federal de Minas GeraisUFMG, 2016-03-31)
Amphotericin B (AmB), a polyene macrolide antibiotic, is one of the most effective antifungal drug for the treatment of systemical fungal infecction. However, its use is often limited by the occurrence of adverse events, ...
Noncrystalline uric acid inhibits proteoglycan and glycosaminoglycan synthesis in distal tubular epithelial cells (MDCK)
(Associação Brasileira de Divulgação Científica, 2010-10-01)
Hyperuricemia is associated with renal stones, not only consisting of uric acid (UrAc) but also of calcium oxalate (CaOx). Glycosaminoglycans (GAGs) are well-known inhibitors of growth and aggregation of CaOx crystals. We ...
Alteration in cellular viability, pro-inflammatory cytokines and nitric oxide production in nephrotoxicity generation by Amphotericin B: Involvement of PKA pathway signaling
(2013-10-11)
Amphotericin B is one of the most effective antifungal agents; however, its use is often limited owing to adverse effects, especially nephrotoxicity. The purpose of this study was to evaluate the effect of inhibiting the ...