The inactivation of tumour suppressor genes by aberrant methylation of promoter regions has been described as a frequent event in neoplasia development, including lung cancer. The p16 gene is a tumour suppressor gene ...

INTRODUCTION: Carcinoma metastasis to bone is a common reason for consultation to orthopedic surgeons. The presence of bone metastases (BM) is usually associated with poor prognosis which is worsened in the presence of ...

Lung cancer is the leading oncological cause of death in the world. As for carcinomas, they represent between 90% and 95% of lung cancers; among them, non-small cell lung cancer is the most common type and the large cell ...

O diagnóstico diferencial entre a variante pequenas células do carcinoma epidermoide e do carcinoma de pequenas células nem sempre é fácil. Apesar de os descritores alertarem que o primeiro deva manter suas características ...

Metabolomics based on untargeted flow infusion electrospray ionization high-resolution mass spectrometry (FIE-HRMS) can provide a snap-shot of metabolism in living cells. Lung Squamous Cell Carcinoma (SCC) is one of the ...

Allelic Losses on the short arm of chromosome 8 (8p) have been reported as frequent events in several cancers, including Lung. However, no comprehensive mapping analysis of chromosome 8p in Lung cancer tumors has been ...