Buscar
Mostrando ítems 1-10 de 219
Basal-like progenitor cells: A review of dysplastic alveolar regeneration and remodeling in lung repair
Despite the central importance of the respiratory system, the exact
mechanisms governing lung repair after severe injury remain unclear. The notion that alveolar type 2 cells (AT2s) self-renew and
differentiate into ...
Histologic and functional evaluation of lungs reconditioned by ex vivo lung perfusion
(ELSEVIER SCIENCE INCNEW YORK, 2012)
BACKGROUND: Only about 15% of donor lungs are considered suitable for transplantation (LTx). Ex vivo lung perfusion (EVLP) has been developed as a method to reassess and repair damaged lungs. We report our experience with ...
Base Excision Repair Activities Differ in Human Lung Cancer Cells and Corresponding Normal Controls
(INT INST ANTICANCER RESEARCH, 2010)
Oxidative damage to DNA is thought to play a role in carcinogenesis by causing Mutations, and indeed accumulation of oxidized DNA bases has been observed in samples obtained from tumors but not from surrounding tissue ...
Epithelial mesenchymal transition in fibroblastic foci of different fibrosing lung diseases: Repair or remodeling?
(European Respiratory Soc Journals Ltd, 2013-09-01)
Bone Marrow Mononuclear Cell Therapy Led to Alveolar-Capillary Membrane Repair, Improving Lung Mechanics in Endotoxin-Induced Acute Lung Injury
(COGNIZANT COMMUNICATION CORP, 2010)
The aim of this study was to test the hypothesis that bone marrow mononuclear cell (BMDMC) therapy led an improvement in lung mechanics and histology in endotoxin-induced lung injury. Twenty-four C57BL/6 mice were randomly ...
Amicus or adversary: platelets in lung biology, acute injury, and inflammation
(American Thoracic Society, 2019)
Comparison of molecular changes in lung cancers in HIV-positive and HIV-indeterminate subjects
(AMER MEDICAL ASSOC, 1998)
Context.-Human immunodeficiency virus (HIV) infection has been associated with an increasing incidence of malignancy, and HIV-infected persons have an increased incidence of primary lung carcinoma compared with the general ...
Simple Sequence Repeats Together with Mismatch Repair Deficiency Can Bias Mutagenic Pathways in Pseudomonas aeruginosa during Chronic Lung Infection
(Public Library Science, 2013-11-21)
Pseudomonas aeruginosa is an opportunistic pathogen that chronically infects the airways of cystic fibrosis (CF) patients and undergoes a process of genetic adaptation based on mutagenesis. We evaluated the role of ...
Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine-origin influenza type A/H1N1 and acute respiratory failure
(Faculdade de Medicina / USP, 2010)
BACKGROUND: Cases of H1N1 and other pulmonary infections evolve to acute respiratory failure and death when co-infections or lung injury predominate over the immune response, thus requiring early diagnosis to improve ...
Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis
(American Society for Clinical Investigation, 2001-06)
IL-1beta is one of a family of proinflammatory cytokines thought to be involved in many acute and chronic diseases. Although it is considered to participate in wound repair, no major role has been attributed to IL-1beta ...