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Neosaxitoxin, a Paralytic Shellfish Poison toxin, effectively manages bucked shins pain, as a local long-acting pain blocker in an equine model
(Pergamon-Elsevier Science LTD, 2018)
Local anesthesia is an effective method to control pain. Neosaxitoxin is a phycotoxin whose molecular mechanism includes a reversible inhibition of voltage gated sodium channels at the axonal level, impeding nerve impulse ...
First evidence of neosaxitoxin as a long-acting pain blocker in bladder pain syndrome
(Springer, 2015)
Introduction and hypothesis Neosaxitoxin is a phycotoxin
whose molecular mechanism of action shows a reversible
inhibition of voltage-gated sodium channels at the axonal level,
impeding nerve impulse propagation. This ...
Potentiation of local anesthetic activity of neosaxitoxin with bupivacaine or epinephrine: Development of a long-acting pain blocker
(2009)
Local anesthetics effectively block and relieve pain, but with a relatively short duration of action, limiting its analgesic effectiveness. Therefore, a long-acting local anesthetic would improve the management of pain, ...
Gonyautoxins: First evidence in pain management in total knee arthroplasty
(Pergamon-Elsevier Science Ltd., 2016)
Improvements in pain management techniques in the last decade have had a major impact on the practice of total knee arthroplasty (TKA). Gonyautoxin are phycotoxins, whose molecular mechanism of action is a reversible block ...
Evaluation of Neosaxitoxin as a local anesthetic during piglet castration: A potential alternative for Lidocaine
(Elsevier Ltd, 2019)
Objetive: To evaluate Neosaxitoxin (NeoSTX) as a local anesthetic drug, for pain control during and after piglet castration. Study design: Prospective, randomized and double-blind study. Animals: 24 commercial hybrids, ...
Prescripción potencialmente inadecuada de medicamentos en adultos mayores
(Universidad Nacional Mayor de San MarcosPE, 2013)