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Individual differences are critical in determining modafinil-induced behavioral sensitization and cross-sensitization with methamphetamine in mice
(Elsevier B.V., 2012-08-01)
Modafinil is a non-amphetaminic psychostimulant used therapeutically for sleep and psychiatric disorders. However, some studies indicate that modafinil can have addictive properties. the present study examined whether ...
Effects of simultaneous exposure to stress and nicotine on nicotine-induced locomotor activation in adolescent and adult rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-01-01)
Preclinical studies have shown that repeated stress experiences can result in an increase in the locomotor response to the subsequent administration of drugs of abuse, a phenomenon that has been termed behavioral ...
Effects of chronic stress on nicotine-induced locomotor activity and corticosterone release in adult and adolescent rats
(Blackwell Publishing, 2008-03-01)
We examined nicotine-induced locomotion and increase in corticosterone plasma levels in adolescent and adult animals exposed to chronic restraint stress. Adolescent [postnatal day (P) 28-37] and adult (P60-67) rats were ...
Individual differences to repeated ethanol administration may predict locomotor response to other drugs, and vice versa
(Elsevier B.V., 2009-02-11)
Repeated administration of drugs may induce adaptations which affect the behavioral responses to the drug itself or to other drugs. Whether individual characteristics to repeated drug administration predict sensitivity to ...
Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice
(Wiley Blackwell Publishing, Inc, 2008-07)
Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific ...
Temporal and Behavioral Variability in Cannabinoid Receptor Expression in Outbred Mice Submitted to Ethanol-Induced Locomotor Sensitization Paradigm
(Wiley-Blackwell, 2013-09-01)
Background There is a close relationship between the endocannabinoid system and alcoholism. This study investigated possible differential expression of cannabinoid receptors CB1 (CB1R) and CB2 (CB2R) in an outbred mice ...
Differential patterns of expression of neuropeptide Y throughout abstinence in outbred Swiss mice classified as susceptible or resistant to ethanol-induced locomotor sensitization
(Elsevier B.V., 2014-02-01)
Several studies have focused on the negative emotional state associated with drug abstinence. the peptide NPY plays an important role given its involvement in drug addiction, anxiety, and mood disorders. Interestingly, it ...
Repeated administration of caffeine increases femproporex-induced locomotor activity in adolescent and adult rats
(UNIV SAO PAULO, CONJUNTO QUIMICAS, 2008)
Caffeine and femproporex are psychostimulants drugs widely consumed in Brazil. Behavioral sensitization is defined as an augmentation in the behavioral effect of a psychostimulant upon re-administration. Repeated administration ...
Effects of chronic stress on nicotine-induced locomotor activity and corticosterone release in adult and adolescent rats
(Blackwell Publishing, 2008-03-01)
We examined nicotine-induced locomotion and increase in corticosterone plasma levels in adolescent and adult animals exposed to chronic restraint stress. Adolescent [postnatal day (P) 28-37] and adult (P60-67) rats were ...
Effects of simultaneous exposure to stress and nicotine on nicotine-induced locomotor activation in adolescent and adult rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-01-01)
Preclinical studies have shown that repeated stress experiences can result in an increase in the locomotor response to the subsequent administration of drugs of abuse, a phenomenon that has been termed behavioral ...