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Effect of neoadjuvant chemotherapy on low-density lipoprotein (LDL) receptor and LDL receptor-related protein 1 (LRP-1) receptor in locally advanced breast cancer
(Associação Brasileira de Divulgação Científica, 2012)
Low-density lipoprotein (LDL) receptors are overexpressed in most neoplastic cell lines and provide a mechanism for the internalization and concentration of drug-laden nanoemulsions that bind to these receptors. The aim ...
Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis
(Oxford University Press, 2018)
SN-38-loaded nanofiber matrices for local control of pediatric solid tumors after subtotal resection surgery
(Elsevier, 2016-02)
In addition to surgery, local tumor control in pediatric oncology requires new treatments as an alternative to radiotherapy. SN-38 is an anticancer drug with proved activity against several pediatric solid tumors including ...
Bacterial cellulose hydrogel loaded with lipid nanoparticles for localized cancer treatment
(Elsevier Science, 2018-10)
The use of hybrid materials, where a matrix sustains nanoparticles controlling the release of the chemotherapeutic drug, could be beneficial for the treatment of primary tumors prior or after surgery. This localized ...
Topotecan Delivery to the Optic Nerve after Ophthalmic Artery Chemosurgery
(Public Library of Science, 2016-03)
Extraocular retinoblastoma is a major challenge worldwide, especially in developing countries. Current treatment involves the administration of systemic chemotherapy combined with radiation, but there is a clear need for ...
Promising nanotherapy in treating leishmaniasis
(2018-08-25)
Leishmaniases are infectious diseases caused by an intracellular protozoan in humans by 20 different species of Leishmania among more than 53 species. There are at least twelve million cases of infections worldwide and ...