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The Antimicrobial Peptide LL-37 as a Possible Adjunct for the Proliferation and Differentiation of Dental Pulp Stem Cells
(2017-12-01)
Introduction This study evaluated the biocompatibility of 5 and 10 μg/mL LL-37 in vitro and its effect on the differentiation of human dental pulp stem cells (DPSCs) into odontoblast-like cells. Methods Cell viability, ...
LL37 peptide@silver nanoparticles: combining the best of the two worlds for skin infection control
(Royal Society of Chemistry, 2014-04)
Capping silver nanoparticles with LL37 peptide eradicates the antiproliferative effect of silver on primary skin cells, but retains the bactericidal properties of silver nanoparticles with activities comparable to silver ...
Smoking reduces cathelicidin LL-37 and human neutrophil peptide 1–3 levels in the gingival crevicular fluid of patients with periodontitis
(2020-01-01)
Background: Antimicrobial peptides are components of innate immune response that have a key role on susceptibility and resistance of the oral cavity to diseases. This study aimed to investigate the influence of smoking on ...
Haematological, biochemical and immunological biomarkers, antibacterial activity, and survival in Nile tilapia Oreochromis niloticus after treatment using antimicrobial peptide LL-37 against Streptococcus agalactiae
(2021-02-25)
Among the antimicrobial peptides (AMPs), which act as natural antibiotics in preventing the colonization of pathogens, LL-37 is noteworthy. It is a human cathelicidin characterized as a broad-spectrum antibiotic, with ...
Antimicrobial peptides in saliva of children with severe early childhood caries
(2016-09-01)
Objective Controversies exist regarding the relationship between the concentrations of antimicrobial peptides (AMPs) and presence of dental caries in children. Thus, the aim of this study was to examine levels of AMPs in ...
Effect of analogues of cationic peptides on dentin mineralization markers in odontoblast-like cells
(2019-07-01)
Objectives: To evaluate the effect of analogues of cationic peptides on the viability and the expression of phenotypic and genotypic markers of dentin mineralization in MDPC-23 odontoblast-like cells. Materials and methods: ...
Antimicrobial peptides and nitric oxide production by neutrophils from periodontitis subjects
(Associação Brasileira de Divulgação Científica, 2012)
Neutrophils play an important role in periodontitis by producing nitric oxide (NO) and antimicrobial peptides, molecules with microbicidal activity via oxygen-dependent and -independent mechanisms, respectively. It is ...
Association of vitamin D3, VDR gene polymorphisms, and LL-37 with a clinical form of Chagas Disease
(Sociedade Brasileira de Medicina Tropical - SBMT, 2019)
AbstractINTRODUCTION:Chagas disease (CD) is an important public health problem in Brazil and worldwide. Aging and obesity are important matters in patients with CD, as is hypovitaminosis D3, which can decrease the quality ...