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Preparation of a novel lipid-core micelle using a low-energy emulsification method
(Springer Verlag, 2018)
High-energy methods for the manufacturing of nanomedicines are widely used; however, interest in low-energy methods is increasing due to their simplicity, better control over the process, and energy-saving characteristics ...
Drug-loaded lipid-core micelles in mucoadhesive films as a novel dosage form for buccal administration of poorly water-soluble and biological drugs
(MDPI, 2020)
The aim of the study was to develop a novel buccal dosage form to transport rhodamine 123 and human insulin as models for poorly water-soluble and biological drugs, using lipid-core micelles (LCMs)-loaded mucoadhesive ...
Ethidium bromide and SYBR Green I interact with lipid micelles
(OMICS International, 2017-03)
Ethidium Bromide and SYBR Green I are usual examples of ligands that specifically binds to DNA by intercalation. Here we describe that micelles of gangliosides, a lipidic family of sialoglycosphingolipids which are the ...
Lipid-Core Nanocapsules as a Nanomedicine for Parenteral Administration of Tretinoin: Development and In Vitro Antitumor Activity on Human Myeloid Leukaemia Cells
(Amer Scientific PublishersStevenson RanchEUA, 2010)
Spectroscopic characterization and general features of piroxicam encapsulated in nanostructured lipid carriers
(Elsevier Science, 2021-05)
A detailed and unique spectroscopic study was developed to understand the interaction between an active principle and a lipid based-drug delivery system. Nanostructured lipid carrier (NLCs) loaded with piroxicam (PX) was ...
Insights on the structure-activity relationship of peptides derived from Sticholysin II
(Wiley-Blackwell, 2018-09-01)
Sticholysin II (StII) is a pore-forming actinoporin from the sea anemone Stichodactyla helianthus. A mechanistic model of its action has been proposed: proteins bind to cell membrane, insert their N-termini into the lipid ...
Desarrollo de nanosuspensiones como tintas para impresión de fármacos de baja solubilidad acuosa
(Universidad de Chile, 2017)
Los fármacos de baja solubilidad acuosa (BCS clase II y IV) presentan un desafío para ser formulados. Dentro de las nuevas formas de entrega de fármaco, y que pueden ser utilizadas para este tipo de fármacos, la impresión ...
Aproximaciones al diseño de copolímeros anfifílicos con potencial aplicación en la encapsulación y liberación de Anfotericina B
(Departamento de QuímicaUniversidad Nacional de Colombia - Sede Bogotá, 2019-07-19)
En este estudio, se describe la síntesis de copolímeros anfifílicos de PEG-b-PCL bioconjugados con colesterol o retinol del tipo AB y ABA a través de polimerización por apertura de anillo (ROP) y esterificación de Steglich. ...
Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile21)-Ha Peptide from Hypsiboas albopunctatus
(2013-04-09)
Antimicrobial peptides (AMPs) isolated from several organisms have been receiving much attention due to some specific features that allow them to interact with, bind to, and disrupt cell membranes. The aim of this paper ...
Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile21)-Ha Peptide from Hypsiboas albopunctatus
(2013-04-09)
Antimicrobial peptides (AMPs) isolated from several organisms have been receiving much attention due to some specific features that allow them to interact with, bind to, and disrupt cell membranes. The aim of this paper ...