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Lipid nanoparticles for the topical delivery of retinoids and derivatives
(Future Medicine Ltd., 2015)
Retinoids are lipophilic compounds that are highly used in cosmetics/therapeutics for skin disorders. Conventional formulations are limited by poor water solubility, high chemical/photochemical instability and the irritation ...
Nanotechnology-based lipid systems applied to resistant bacterial control: A review of their use in the past two decades
(2021-06-15)
The rate of infections caused by resistant bacteria to the antimicrobials available for human use grows exponentially every year, which generates major impacts on human health and the world economy. In the last two decades, ...
Self-assembled nanomaterials
(Elsevier, 2017)
Therapeutically effective and biocompatible nanomaterials based on polymer and lipid carriers, continuously lead researchers to design novel tools and strategies. Because of their potential ability to improve current ...
Characterization of Articaine-Loaded Poly(epsilon-caprolactone) Nanocapsules and Solid Lipid Nanoparticles in Hydrogels for Topical Formulations
(Amer Scientific Publishers, 2018-06-01)
This work describes the development of poly-epsilon-caprolactone nanocapsules (PCL-NC) and solid lipid nanoparticles (SLN) aiming delivery for articaine (ATC), in order to improve its chemical stability in semi-solid ...
Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery
(Elsevier, 2013)
Here we report the development of new drug nanocarriers – named hyaluronan nanocapsules – for the
intracellular delivery of hydrophobic anticancer drugs. These nanocapsules are composed of a lipid core
and a shell of ...
Lipid-Core Nanocapsules as a Nanomedicine for Parenteral Administration of Tretinoin: Development and In Vitro Antitumor Activity on Human Myeloid Leukaemia Cells
(Amer Scientific PublishersStevenson RanchEUA, 2010)
Hemocompatibility of poly(epsilon-caprolactone) lipid-core nanocapsules stabilized with polysorbate 80-lecithin and uncoated or coated with chitosan
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The hemocompatibility of nanoparticles is of critical importance for their systemic administration as drug delivery systems. Formulations of lipid-core nanocapsules, stabilized with polysorbate 80-lecithin and uncoated or ...
Triamcinolone acetonide-loaded lipid nanocapsules for ophthalmic applications
(Elsevier Science, 2020-01)
Triamcinolone acetonide (TA) is an effective drug widely (off-label) used in the treatment of several ocular diseases involving inflammation and angiogenic processes. However, the use of TA ocular presents some limitations ...
Novel hybrid lipid nanocapsules loaded with a therapeutic monoclonal antibody – Bevacizumab – and Triamcinolone acetonide for combined therapy in neovascular ocular pathologies
(Elsevier Science, 2021-02)
The aim of this study was to design and develop a novel hybrid formulation based on lipid nanocapsules containing bevacizumab (BVZ), an effective therapeutic antibody, on the surface and triamcinolone acetonide (TA) in the ...
Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma
(Elsevier Science, 2015-11)
In this work, multifunctional lipid nanocapsules (M-LNC) were designed to combine the activity of the cytotoxic drug paclitaxel (PTX) with the immunostimulant CpG. This nanosystem, consisting of modified lipid nanocapsules ...