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Comparative investigation of the cleavage step in the synthesis of model peptide resins: Implications for N-alpha-9-fluorenylmethyloxycarbonyl-solid phase peptide synthesis
(Pharmaceutical Soc Japan, 2007-03-01)
Based on our studies of the stability of model peptide-resin linkage in acid media, we previously proposed a rule for resin selection and a final cleavage protocol applicable to the N-alpha-tert-butyloxycarbonyl (Boc)-peptide ...
Comparative investigation of the cleavage step in the synthesis of model peptide resins: Implications for N-alpha-9-fluorenylmethyloxycarbonyl-solid phase peptide synthesis
(Pharmaceutical Soc Japan, 2007-03-01)
Based on our studies of the stability of model peptide-resin linkage in acid media, we previously proposed a rule for resin selection and a final cleavage protocol applicable to the N-alpha-tert-butyloxycarbonyl (Boc)-peptide ...
Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length
(Molecular Diversity Preservation International, 2017-07)
A set of lipopeptides was recently reported for their broad-spectrum antiviral activity against viruses belonging to the Paramyxoviridae family, including human parainfluenza virus type 3 and Nipah virus. Among them, the ...
Modification of the linker amino acid in the cell-penetrating peptide NickFect55 leads to enhanced pDNA transfection for in vivo applications
(MDPI, 2023-02-20)
Despite numerous efforts over the last three decades, nucleic acid-based therapeutics still lack delivery platforms in the clinical stage. Cell-penetrating peptides (CPPs) may offer solutions as potential delivery vectors. ...
Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel
(Elsevier B.V., 2006-08-20)
The peptide pIV/S4-S5 encompasses the cytoplasmic linker between helices S4-S5 in domain IV of the voltage-gated Na+ channel, residues 1644-1664. (2)The interaction of two local anesthetics (LA), lidocaine and benzocaine, ...
Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel
(Elsevier Science BvAmsterdamHolanda, 2006)
A novel activating effect of the regulatory subunit of protein kinase A on catalytic subunit activity
(Elsevier Science Inc, 2008-12)
The strength of the interaction between the catalytic and regulatory subunits in protein kinase A differs among species. The linker region from regulatory subunits is non-conserved. To evaluate the participation of this ...
Comparative molecular docking analysis among six scFv monoclonal antibodies against hepatitis B virus surface antigen
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)