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Genome diversity, recombination, and virulence across the major lineages of Paracoccidioides
(2016-09-01)
The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic to Latin America. To examine the genome evolution ...
Genome Diversity, Recombination, and Virulence across the Major Lineages of Paracoccidioides
(Amer Soc Microbiology, 2016-09-01)
The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic to Latin America. To examine the genome evolution ...
Global phylodynamics of Echovirus 30 revealed differential behavior among viral lineages
(Academic Press Inc Elsevier Science, 2019-05)
Echovirus 30 (E30) is an important causative agent of aseptic meningitis worldwide. Despite this, the global and regional dispersion patterns, especially in South America, are still largely unknown. We performed an in-depth ...
Genome diversity, recombination, and virulence across the major lineages of Paracoccidioides
(2016)
The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic to Latin America. To examine the genome evolution ...
The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci
(eLife Sciences Publications, 2021)
Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core genome loci by interspecies homologous recombinations, and acquisition of gene cassettes. Both occurred in the otherwise contrasting ...
Genomic mosaicism in two strains of Dengue virus type 3
(Elsevier ScienceAmsterdam, 2013-08)
Recombination is a significant factor driving genomic evolution, but it is not well understood in Dengue virus. We used phylogenetic methods to search for recombination in 636 Dengue virus type 3 (DENV-3) genomes and ...
Expression, purification, and biochemical characterization of recombinant DNA polymerase beta of the Trypanosoma cruzi TcI lineage: requirement of additional factors and detection of phosphorylation of the native form
(Springer, 2015)
Chagas disease, caused by the protozoan
Trypanosoma cruzi, is a major parasitic disease that affects
millions of people in America. However, despite the high
impact of this disease on human health, no effective and ...
Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages
(BioMed Central, 2016)
BACKGROUND: Approximately 10% of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families ...