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(+/-)-Licarin A and its semi-synthetic derivatives: In vitro and in silico evaluation of trypanocidal and schistosomicidal activities
(Elsevier B.V., 2020-02-01)
This paper reports the synthesis of (+/-)-licarin A 1, a dihydrobenzofuran neolignan, resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme. Following, three semi-synthetic ...
Schistosomicidal and trypanocidal structure-activity relationships for (+/-)-licarin A and its (-)- and (+)-enantiomers
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
(+/-)-Licarin A (1) was obtained by oxidative coupling, and its enantiomers, (-)-licarin A (2) and (+)-licarin A (3), were resolved by chiral HPLC. Schistosomicidal and trypanocidal activities of these compounds were ...
Enantiomeric resolution of (+/-)-licarin A by high-performance liquid-chromatography using a chiral stationary phase
(ELSEVIER SCIENCE BV, 2011)
(+/-)-Licarin A (1), a neolignan obtained by the oxidative coupling reaction of isoeugenol, had in this study its enantiomers resolved. A novel, quick and efficient enantiomeric resolution of 1 was directly performed by ...
Stereoselective synthesis of 8,9-licarinediols
(Elsevier B.V., 2000-11-17)
The total synthesis of 8,9-licarinediols was selectively carried out from licarin A, previously obtained by oxidative coupling of (E)-isoeugenol. The corresponding enantiomerically pure (+)- and(-)-licarin A ester derivatives ...
Stereoselective synthesis of 8,9-licarinediols
(Elsevier B.V., 2000-11-17)
The total synthesis of 8,9-licarinediols was selectively carried out from licarin A, previously obtained by oxidative coupling of (E)-isoeugenol. The corresponding enantiomerically pure (+)- and(-)-licarin A ester derivatives ...
Stereoselective synthesis of 8,9-licarinediols
(Elsevier B.V., 2014)
Relação estrutura/atividade entre lignanas e mecanismos envolvidos na vasodilatação em aorta de camundongo
(Universidade Federal de Minas GeraisUFMG, 2013-07-05)
Studies have shown that lignans have properties beneficial to the cardiovascular system, showing an anti-hypertensive, vasodilator and protective vascular action. The structure-activity relationship and the mechanism of ...
Constituents of the Leaves of Magnolia ovata
(AMER CHEMICAL SOC, 2009)
Two new lignans, magnovatins A (1) and B (2), along with nine known compounds, were isolated from the leaves of Magnolia ovata. The known compounds were identified as acuminatin (3), licarin A (4), kadsurenin M, ...
Essential Oil and other Constituents from Magnolia ovata Fruit
(NATURAL PRODUCTS INCWESTERVILLE, 2013-08-02)
The volatile and non-volatile constituents of the unripe fruits of Magnolia ovata (A. St.-Hil.) Spreng. (Magnoliaceae) were studied. The essential oils were obtained by hydrodistillation of the fruit of two plant populations ...