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Biological and conformational evaluation of angiotensin II lactam bridge containing analogues

Oliveira Junior, Vani Xavier; Fázio, Marcos Antonio [UNIFESP]; Silva, Adriana Farias; Campana, Patricia Targon; Pesquero, João Bosco [UNIFESP]; Santos, Edson Lucas; Costa-Neto, Cláudio Miguel; Miranda, Antonio [UNIFESP] (Elsevier B.V., 2011-12-10)

Angiotensin II (All) is the active octapeptide product of the renin enzymatic cascade, which is responsible for sustaining blood pressure. in an attempt to establish the All-receptor-bound conformation of this octapeptide, ...

The Importance of Ring Size and Position for the Antiplasmodial Activity of Angiotensin II Restricted Analogs

Torres, Marcelo Der Torossian; Silva, Adriana Farias; Alves, Flavio Lopes [UNIFESP]; Capurro, Margareth Lara [UNIFESP]; Miranda, Antonio [UNIFESP]; Oliveira Junior, Vani Xavier (Springer, 2014-09-01)

Malaria is caused by the protozoa Plasmodium and is responsible for approximately one million deaths annually. the antimalarial effects of angiotensin II and its analogs against Plasmodium gallinaceum and falciparum have ...

Molecular Graphics Approach To Bacterial Acrb Protein-beta-lactam Antibiotic Molecular Recognition In Drug Efflux Mechanism.

Kiralj, Rudolf; Ferreira, Márcia M C (2006)

A study of the anti-plasmodium activity of angiotensin II analogs

Chamlian, Mayra; Bastos, Erick Leite; Miranda, Ceres Maciel de; Guimaraes, Margareth de Lara Capurro; Miranda, Antonio; Silva, Adriana F.; Torres, Marcelo Der T.; Oliveira Jr, Vani X. (John Wiley & SonsChichester, 2013-09)

Controlling the dissemination of malaria requires the development of new drugs against its etiological agent, a protozoan of the Plasmodium genus. Angiotensin II and its analog peptides exhibit activity against the development ...

Synthesis of lactam-bridged and lipidated cyclo-peptides as promising anti-phytopathogenic agents

Vasco, Aldrin V.; Brode, Martina; Méndez, Yanira; Valdés-Lizama, Oscar; Rivera, Daniel G.; Wessjohann, Ludger A. (2023)

Relação estrutura-atividade da galanina e de alguns de seus análogos

Marra, Marcus (Universidade Federal de São Paulo (UNIFESP), 2009-04-29)

Galanin (Gal1-29-NH2) is a 29-amino-acid neuropeptide (GWTLNSAKGLLGPHAID NHRSFHDKYGLA-NH2) which was originally isolated from the porcine gut. Gal1-29-NH2 has been involved in multiple physiological functions including ...

Qsar Study Of β-lactam Antibiotic Efflux By The Bacterial Multidrug Resistance Pump Acrb

Ferreira M.M.C.; Kiralj R. (, 2004)

Antimicrobial Susceptibility Testing for Enterococci

Khan, Ayesha; Miller, William; Axell, Dierdre; Munita, José; Ariasb, Cesar (2022)

Enterococci are major, recalcitrant nosocomial pathogens with a wide repertoire of intrinsic and acquired resistance determinants and the potential of developing resistance to all clinically available antimicrobials. As ...

Molecular Graphics Approach To Bacterial Acrb Protein-β-lactam Antibiotic Molecular Recognition In Drug Efflux Mechanism

Kiralj R.; Ferreira M.M.C. (, 2006)

Farmacocinética poblacional en el manejo empírico de infecciones en pacientes con neoplasias hematológicas y neutropenia febril pos-quimioterapia

Parra González, Daniel Sebastián (Universidad Nacional de ColombiaBogotá - Ciencias - Maestría en Ciencias - FarmacologíaDepartamento de FarmaciaFacultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021)

Los pacientes con neoplasias hematológicas y neutropenia febril postquimioterapia podrían presentar alteraciones fisiológicas que lleven a cambios en la farmacocinética (PK) de los fármacos comparado a individuos sin cáncer ...