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Mixed-Ligand Complexes of Technetium and Rhenium with Tridentate Benzamidines and Bidentate Benzoylthioureas
(WILEY-V C H VERLAG GMBH, 2009)
Mixed-ligand complexes of technetium(V) or rhenium(V) containing tridentate N-[(dialkylamino)(thiocarbonyl)]benzamidine (H(2)L(1)) and bidentate N,N-dialkyl-N`-benzoylthiourea (HL(2)) ligands were formed in high yields ...
Synthesis of biphenyl-based arsine ligands by Suzuki-Miyaura coupling and their application to Pd-catalyzed arsination
(Royal Society of Chemistry, 2011-09)
A versatile and efficient approach for the synthesis of new biphenyl-based arsine ligands, by a Pd-catalyzed arsination to introduce the -AsPh2 moiety, and then a Suzuki-Miyaura cross-coupling for biaryl construction is ...
Natural products biological screening and ligand-based virtual screening for the discovery of new antileishmanial agents
(BENTHAM SCIENCE PUBL LTD, 2008)
In the course of our research program to discover novel antileishmanial agents, a biological screening of natural products against Leishmania major promastigotes allowed the identification of a furoquinoline alkaloid (1) ...
Comparing and combining implicit ligand sampling with multiple steered molecular dynamics to study ligand migration processes in heme proteins
(John Wiley & Sons Inc, 2011-07)
The ubiquitous heme proteins perform a wide variety of tasks that rely on the subtle regulation of their affinity for small ligands like O2, CO, and NO. Ligand affinity is characterized by kinetic association and dissociation ...
A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain
(Elsevier B.V., 2004-08-06)
Literature studies, 3D structure data, and a series of sequence analysis techniques were combined to reveal important residues in the structure and function of the ligand-binding domain of nuclear hormone receptors. A ...
Structure- and ligand-based drug design approaches for neglected tropical diseases
(INT UNION PURE APPLIED CHEMISTRYRES TRIANGLE PK, 2012)
Drug discovery has moved toward more rational strategies based on our increasing understanding of the fundamental principles of protein-ligand interactions. Structure( SBDD) and ligand-based drug design (LBDD) approaches ...
Ligand effects on the optical and chiroptical properties of the thiolated Au18cluster
(Royal Society of Chemistry, 2016)
Capillary bioreactors based on human purine nucleoside phosphorylase: A new approach for ligands identification and characterization
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The enzyme purine nucleoside phosphorylase (PNP) is a target for the discovery of new lead compounds employed on the treatment severe T-cell mediated disorders. Within this context, the development of new, direct, and ...
Effect of amine ligands on stabilization of pt nanoparticles as electrode materials for electro-oxidation of methanol
(Journal of New Materials for Electrochemical Systems Volume 14, Issue 1, 2011, Pages 1-10, 2011)
Pt-stabilized catalysts with platinum crystallites sizes between 1-20 nm were prepared using an organometallic approach and three different amino ligands; tert-butylamine, 1,3-diaminopropane and anthranilic acid. The ...