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Modern drug discovery technologies: opportunities and challenges in lead discovery
(Bentham ScienceBussum, 2011-12)
The identification of promising hits and the generation of high quality leads are crucial steps in the early stages of drug discovery projects. The definition and assessment of both chemical and biological space have ...
In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery
(Frontiers Media, 2020)
How has the genomics era impacted schistosomiasis drug discovery?
(Future Science, 2016)
Computational chemistry in drug lead discovery and design
(John Wiley & Sons Inc., 2019-01)
The main contributions of our group during the last 15 years developing and using biomolecular simulation tools in drug lead discovery and design, in close collaboration with experimental researchers, are presented. Special ...
Aptamers: current challenges and future prospects
(Informa Healthcare, 2015-12)
Introduction: Aptamers are oligonucleotide molecules raised in vitro from large combinatorial libraries of nucleic acids and developed to bind to targets with high affinity and specificity. Whereas novel target molecules ...
Paths to the discovery of antivenom serotherapy in France
(BioMed Central, 2023)
Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence
(Frontiers Media, 2021)
Can the false-discovery rate be misleading?
(Wiley, 2018)