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NAD Biosynthesis Evolution in Bacteria: Lateral Gene Transfer of Kynurenine Pathway in Xanthomonadales and Flavobacteriales
(OXFORD UNIV PRESS, 2009)
The biosynthesis of quinolinate, the de novo precursor of nicotinamide adenine dinucleotide (NAD), may be performed by two distinct pathways, namely, the bacterial aspartate (aspartate-to-quinolinate) and the eukaryotic ...
Kynurenines in the Pathogenesis of Peripheral Neuropathy During Leprosy and COVID-19
(Frontiers Media, 2022)
Towards an insight on photodamage in hair fibre by UV-light: An experimental and theoretical study
(2013-06-27)
Synopsis: Objectives: In this research, an experimental and theoretical study was conducted to design a photodegradation mechanism of the amino acid tryptophan (Trp) in hair fibres. Methods: For the experimental research, ...
A First Plasmodium vivax Natural Infection Induces Increased Activity of the Interferon Gamma-Driven Tryptophan Catabolism Pathway
(Frontiers Media, 2020)
The human immune response that controls Plasmodium infection in the liver and blood stages of the parasite life cycle is composed by both pro- and anti-inflammatory programs. Pro-inflammatory responses primarily mediated ...
Changes in synaptic transmission and protein expression in the brains of adult offspring after prenatal inhibition of the kynurenine pathway
(Elsevier, 2013-10)
During early brain development, N-methyl-D-aspartate (NMDA) receptors are involved in cell migration, neuritogenesis, axon guidance and synapse formation, but the mechanisms which regulate NMDA receptor density and function ...
Análise de polimorfismos dos genes da rota quinurenina em pacientes com meningite bacteriana.
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Genética e Biologia MolecularGenética e Biologia Molecular, 2008-03-28)
Bacterial meningitis (BM) is still an important infectious disease causing death and disability. Invasive bacterial infections of the central nervous systems (CNS) generate some of the most powerful ...
Towards an insight on photodamage in hair fibre by UV-light: An experimental and theoretical study
(2013-06-27)
Synopsis: Objectives: In this research, an experimental and theoretical study was conducted to design a photodegradation mechanism of the amino acid tryptophan (Trp) in hair fibres. Methods: For the experimental research, ...
Metabolites of the Kyn pathway participate in the control of the T. cruzi infection in human placental explants
(Elsevier Science Inc, 2019)
Objective: to evaluate the effect of the kynurenine (Kyn) pathway (KP) metabolites at controlling the infection by Trypanosoma cruzi in human placental explants.